ACET-(4-N-HEXYL)ANILID

Base Information

• Chemical Name: ACET-(4-N-HEXYL)ANILID
• CAS No.: 20330-59-0
• Molecular Formula: C14H21 N O
• Molecular Weight: 219.327
• Hs Code.: 2924299090
• Mol file: 20330-59-0.mol

Synonyms:Acetanilide,4'-hexyl- (6CI,8CI); 4'-Hexylacetanilide; p-n-Hexylacetanilide

Chemical Property of ACET-(4-N-HEXYL)ANILID

Chemical Property:

• Melting Point: 89-91°C
• PSA: 29.10000
• LogP: 3.84080

Purity/Quality:

98%Min ^*data from raw suppliers

ACET-(4-N-HEXYL)ANILIDE 98.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of ACET-(4-N-HEXYL)ANILID

There total 14 articles about ACET-(4-N-HEXYL)ANILID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

1-(4-hexyl-phenyl)-ethanone (37592-72-6) → N-(4-hexylphenyl)acetamide (20330-59-0)

Guidance literature:

With sodium azide; sulfuric acid; In acetic acid; at 60 - 70 ℃; for 5h;

Reference yield: 73.0%

N-(4-(2-cyanohexyl)phenyl)acetamide → N-(4-hexylphenyl)acetamide (20330-59-0)

Guidance literature:

With di-tert-butyl peroxide; (1,3-dimethylimidazol-2-ylidene)borane; In tert-butyl methyl ether; at 120 ℃; for 48h; Inert atmosphere;

DOI:10.1021/acs.joc.0c00105

Reference yield: 12.0%

1-hexene (592-41-6,25067-06-5) + 4-Acetamido-1-iodobenzene (622-50-4) → N-(4-hexylphenyl)acetamide (20330-59-0) + N-(4-heptylphenyl)acetamide (20330-65-8) + N-(4-octylphenyl)acetamide (37593-11-6) + N-(4-nonylphenyl)acetamide (37593-12-7) + N-(4-decylphenyl)acetamide (37593-13-8) + N-(4-butylphenyl)acetamide (3663-20-5) + N-(4-pentylphenyl)acetamide (20330-52-3) + N-(4-undecylphenyl)acetamide (102707-88-0) + N-acetyl-4-n-dodecylaniline (3663-30-7) + N-(4-tridecylphenyl)acetamide (68777-64-0) + N-(4-tetradecylphenyl)acetamide (72755-62-5)

Guidance literature:

1-hexene; With tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride; at 70 ℃; for 12h; Inert atmosphere; Sealed tube;

With Schwartz's reagent; In tetrahydrofuran; at 50 ℃; for 5h; Inert atmosphere; Sealed tube;

4-Acetamido-1-iodobenzene; With 4,4'-di-tert-butyl-2,2'-bipyridine nickel(II) bromide; tetrabutylammonium p-toluenesulfonate; In tetrahydrofuran; at 20 ℃; for 24h; Inert atmosphere; Irradiation; Sealed tube;

DOI:10.1016/j.chempr.2019.12.010

upstream raw materials:

4-hexylaniline

1-(4-hexyl-phenyl)-ethanone

1-bromo-hexane

hexylbenzene

Downstream raw materials:

C₄₀H₄₈Br₂N₄O₂

2,2'-bipyridyl-6,6'-dicarboxylic acid N,N'-diethyl-N,N'-di(4-hexylphenyl)amide

N-ethyl(4-hexyl)aniline

diamino-1,2 n-hexyl-4 benzene

Refernces

• 1、 Kawamoto, Takuji,Oritani, Kyohei,Kawabata, Atsushi,Morioka, Tsubasa,Matsubara, Hiroshi,Kamimura, Akio. "Hydrodecyanation of Secondary Alkyl Nitriles and Malononitriles to Alkanes using DiMeImd-BH3". . p. 6137 - 6142. Retrieved 2020/05/22.
• 2、 Krati, Noureddine,Roizard, Denis,Brembilla, Alain,Lochon, Pierre. "Nouveaux diamino-3,4 phenylalcanes et leur transformation en benzimidazolemethanethiols-2". . p. 443 - 448. Retrieved 2007/10/02.