(+/-)-isomenthone oxime

Base Information

• Chemical Name: (+/-)-isomenthone oxime
• CAS No.: 21002-69-7
• Molecular Formula: C₁₀H₁₉NO
• Molecular Weight: 169.267
• Mol file: 21002-69-7.mol

Synonyms:

Chemical Property of (+/-)-isomenthone oxime

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (+/-)-isomenthone oxime

There total 7 articles about (+/-)-isomenthone oxime which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

2-(2-isopropyl-5-methylcyclohexyloxy)tetrahydro-2H-pyran (72020-06-5,80924-03-4,97526-56-2,123121-06-2,128946-28-1,128946-29-2,128946-30-5,128946-31-6,134052-28-1) → p-menthan-3-one oxime (1198-91-0,21002-69-7,26134-50-9,37886-68-3,49775-31-7,49805-45-0,49805-46-1,49805-47-2,65620-72-6,114129-78-1,19096-86-7,165874-36-2)

Guidance literature:

With trichloroisocyanuric acid; hydroxylamine hydrochloride; In neat (no solvent); at 110 ℃; for 1h; Green chemistry;

DOI:10.1080/10426507.2014.990015

Reference yield: 73.0%

(2-isopropyl-5-methylcyclohexyloxy)trimethylsilane (62338-23-2,66808-39-7,88390-70-9,122999-13-7,18419-38-0) → p-menthan-3-one oxime (1198-91-0,21002-69-7,26134-50-9,37886-68-3,49775-31-7,49805-45-0,49805-46-1,49805-47-2,65620-72-6,114129-78-1,19096-86-7,165874-36-2)

Guidance literature:

With trichloroisocyanuric acid; hydroxylamine hydrochloride; In neat (no solvent); at 100 ℃; for 3.25h; Green chemistry;

DOI:10.1080/10426507.2014.990015

Reference yield:

acetylhydroxamic acid (546-88-3) + Menthone (10458-14-7,17627-49-5,7786-64-3) → p-menthan-3-one oxime (1198-91-0,21002-69-7,26134-50-9,37886-68-3,49775-31-7,49805-45-0,49805-46-1,49805-47-2,65620-72-6,114129-78-1,19096-86-7,165874-36-2)

Guidance literature:

With boron trifluoride diethyl etherate; In methanol;

DOI:10.1002/adsc.201200036

upstream raw materials:

3-Chlor-3-nitroso-1-methyl-4-isopropyl-cyclohexan

trimethylaluminum

Menthone

acetylhydroxamic acid

Downstream raw materials:

3,7-dimethyloctanoic acid

thymol

[(C₆H₅)3PCH₂C₆H₅]⁽¹⁺⁾*[PtCl₅(NHC(C₂H₅)ONC(C₉H₁₈))]^(1-)=[(C₆H₅)3PCH₂C₆H₅][PtCl₅(NHC(C₂H₅)ONC(C₉H₁₈))]

2-isopropyl-5-methyl-phenylamine

Refernces

• 1、 Madabhushi, Sridhar,Vangipuram, Venkata Sairam,Mallu, Kishore Kumar Reddy,Chinthala, Narsaiah,Beeram, China Ramanaiah. "Europium(III) triflate-catalyzed Trofimov synthesis of polyfunctionalized pyrroles". supporting information; body text. p. 1413 - 1416. Retrieved 2012/07/13.
• 2、 Lub, J.,Beekes, M. L.,Boer, Th. J. de. "C-Nitroso compounds. Part XXXVIII. Radical reactions of α-chloro-nitroso compounds with trialkylaluminium-ether complexes". . p. 161 - 167. Retrieved 2007/10/02.