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Chemical Baike

Strain-Driven Epimerization

Strain-driven epimerization is a concept in organic chemistry that relies on the intrinsic strain or energy associated with a specific conformation of a molecule. When a sugar molecule is forced into a strained conformation, it becomes more susceptible to epimerization at certain chiral centers. This concept can be harnessed to selectively convert one sugar epimer into another.

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