1038915-92-2

Basic information

• Product Name: tert-butyl 3-(4-(7-carbamoyl-2H-indazol-2-yl)phenyl)piperidine-1-carboxylate
• Synonyms: tert-butyl 3-(4-(7-carbamoyl-2H-indazol-2-yl)phenyl)piperidine-1-carboxylate
• CAS NO: 1038915-92-2
• Molecular Weight: 420.511
• Mol File: 1038915-92-2.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: tert-butyl 3-(4-(7-carbamoyl-2H-indazol-2-yl)phenyl)piperidine-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 3-(4-(7-carbamoyl-2H-indazol-2-yl)phenyl)piperidine-1-carboxylate(1038915-92-2)
• EPA Substance Registry System: tert-butyl 3-(4-(7-carbamoyl-2H-indazol-2-yl)phenyl)piperidine-1-carboxylate(1038915-92-2)

Safety Data

• Hazardous Substances Data: 1038915-92-2(Hazardous Substances Data)

Upstream product

• 1038915-90-0 methyl 2-{4-[1-(tert-butoxycarbonyl)piperidin-3-yl]phenyl}-2H-indazole-7-carboxylate 
• 1038915-99-9 tert-butyl 3-[4-({[3-(methoxycarbonyl)-2-nitrophenyl]methylene}amino)phenyl]piperidine-1-carboxylate 
• 5437-38-7 3-methyl-2-nitrobenzoic acid 
• 5471-82-9 methyl 3-methyl-2-nitrobenzoate 
• 138229-59-1 3-formyl-2-nitrobenzoic acid methyl ester 
• 77287-34-4 formamide 
• 134-20-3 2-carbomethoxyaniline 
• 1056971-32-4 tert-butyl-3-phenylpiperidine-1-carboxylate 
• 750585-94-5 2-bromo-3-formyl-benzoic acid methyl ester 
• 875798-79-1 3-(4-aminophenyl)piperidine-1-carboxylic acid tert-butyl ester 
• 132874-06-7 methyl 3-(bromomethyl)-2-nitrobenzoate 

Downstream Products

• 1038915-56-8 racemic 3-{4-[7-(aminocarbonyl)-2H-indazol-2-yl]phenyl}piperidinium chloride 
• 1038915-60-4 (3S)-3-[4-{7-(aminocarbonyl)-2H-indazol-2-yl}phenyl]piperidine 
• 1038915-58-0 2-{4-[(3S)-piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide 

Relevant articles and documents

Indazole formamide compound as well as preparation method and application thereof

The invention belongs to the field of chemical medicines, and particularly relates to an indazole formamide compound as well as a preparation method and application thereof. The invention provides anindazole carboxamide compound or a pharmaceutically acce

Synthesis method for preparing PARP inhibitor Niraparib

The invention provides a novel synthesis method for preparing a PARP inhibitor Niraparib. The method comprises the steps that a starting material methyl anthranilate is subjected to diazo coupling, cyclization, amidation, BOC removal and chiral resolution, and then the Niraparib with the purity reaching 99.5% is obtained. The method is simple, convenient and easy to operate suitable for industrial production.

Synthesis method of novel oral anticancer medicine Nirapairb

The invention discloses a synthesis method of a novel oral anticancer medicine Nirapairb, the method comprises the following steps of subjecting a starting raw material 3-methyl-2-methyl bromobenzoate to a series of reactions of oxidization, aldimine condensation, cyclization, amidation, BOC (tert-Butyloxycarbonyl) removal, chiral separation and the like to obtain optically pure Niraparib of which the purity reaches 98.2 percent. The method is simple to operate, and is applicable to industrialized production; synthesis steps are few; a reaction condition is easily controlled.