1092679-51-0 Usage
Description
WAY100635 is a potent and selective antagonist of serotonin 5-HT1A receptors, characterized by its high affinity and selectivity with an IC50 value of 2.2 nM (Ki = 0.8 nM) for inhibiting 5-HT1A receptors in rat hippocampal membranes. It is also known to exhibit agonist activity at dopamine D4 receptors (Kd = 2.4 nM), making it a valuable compound for studying the interactions between serotonin and dopamine systems.
Uses
Used in Pharmaceutical Research:
WAY100635 is used as a research tool for investigating the role of 5-HT1A receptors in various physiological and pathological processes. Its high selectivity and potency make it an ideal candidate for studying the distribution and function of these receptors in the central nervous system.
Used in Neuropharmacology:
In neuropharmacology, WAY100635 is used as a selective antagonist to explore the interactions between serotonin and dopamine systems. Its agonist activity at dopamine D4 receptors allows researchers to investigate the complex interplay between these neurotransmitter systems and their implications in various neurological and psychiatric disorders.
Used in Drug Development:
WAY100635 serves as a lead compound in the development of new drugs targeting 5-HT1A receptors for the treatment of anxiety, depression, and other mood disorders. Its agonist activity at dopamine D4 receptors also opens up possibilities for the development of drugs addressing dopamine-related conditions such as schizophrenia and Parkinson's disease.
Used in Drug Delivery Systems:
Similar to gallotannin, WAY100635 can be incorporated into novel drug delivery systems to enhance its bioavailability, delivery, and therapeutic outcomes. These systems may include organic and metallic nanoparticles, which can improve the compound's solubility, stability, and targeting capabilities, ultimately leading to more effective treatments for various conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 1092679-51-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,9,2,6,7 and 9 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1092679-51:
(9*1)+(8*0)+(7*9)+(6*2)+(5*6)+(4*7)+(3*9)+(2*5)+(1*1)=180
180 % 10 = 0
So 1092679-51-0 is a valid CAS Registry Number.