1121-79-5 Usage
Description
3-Chloro-6-methylpyridazine is a heterocyclic compound characterized by a pyridazine ring with a chlorine atom at the 3-position and a methyl group at the 6-position. It is a colorless to yellow liquid with unique chemical properties that make it a versatile building block in organic synthesis.
Uses
Used in Pharmaceutical Industry:
3-Chloro-6-methylpyridazine is used as a key intermediate in the preparation of heterocyclic compounds, which serve as integrase inhibiting antiviral agents. These agents are crucial in the development of antiviral medications, providing a means to combat viral infections by inhibiting the integration of viral DNA into the host genome.
Used in Organic Synthesis:
3-Chloro-6-methylpyridazine is utilized as a reactant in nickel-catalyzed cross-coupling reactions with aromatic and heteroaromatic halides. This process allows for the formation of substituted aryland heteroaryl pyridazines, which are valuable building blocks in the synthesis of various pharmaceuticals and agrochemicals.
Used in Medicinal Chemistry:
3-Chloro-6-methylpyridazine can be employed in the synthesis of a p38MAP kinase inhibitor, which holds therapeutic potential in the treatment of autoimmune and inflammatory diseases. By targeting the p38MAP kinase pathway, this inhibitor may help regulate immune responses and alleviate symptoms associated with these conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 1121-79-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,1,2 and 1 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1121-79:
(6*1)+(5*1)+(4*2)+(3*1)+(2*7)+(1*9)=45
45 % 10 = 5
So 1121-79-5 is a valid CAS Registry Number.
InChI:InChI=1/C5H5ClN2/c1-4-2-3-5(6)8-7-4/h2-3H,1H3
1121-79-5Relevant articles and documents
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Ogata,Kano
, p. 1176 (1967)
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Malononitrile compounds as pesticides
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Page/Page column 40, (2010/02/12)
The present invention provides a malononitrile compound represented by the formula (I): The malononitrile compound has an efficient pesticidal activity and can control effectively pests.
Fungicidal pyridazines
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, (2008/06/13)
Plants are protected from the damaging effects of Phycomycetous fungi by a series of pyridazines of formula STR1 wherein R3 is chloro, bromo, methyl, cyano or iodo; R is chloro, bromo, iodo, methyl, cyano or furan-2-ylmethoxy; R1 is
