132486-59-0

Basic information

• Product Name: (+)-(1S,2S)-1,2-diphenyl-1,2-ditosyloxyethane
• Synonyms: (+)-(1S,2S)-1,2-diphenyl-1,2-ditosyloxyethane
• CAS NO: 132486-59-0
• Molecular Weight: 522.643
• Mol File: 132486-59-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (+)-(1S,2S)-1,2-diphenyl-1,2-ditosyloxyethane(CAS DataBase Reference)
• NIST Chemistry Reference: (+)-(1S,2S)-1,2-diphenyl-1,2-ditosyloxyethane(132486-59-0)
• EPA Substance Registry System: (+)-(1S,2S)-1,2-diphenyl-1,2-ditosyloxyethane(132486-59-0)

Safety Data

• Hazardous Substances Data: 132486-59-0(Hazardous Substances Data)

Upstream product

• 2325-10-2 (S,S)-hydrobenzoin 
• 98-59-9 p-toluenesulfonyl chloride 
• 655-48-1 DL-1,2-diphenylethane-1,2-diol 
• 579-43-1 (1S,2R)-1,2-diphenylethane-1,2-diol 

Downstream Products

• 132486-60-3 (-)-(1R,2R)-1,2-diphenylethane-1,2-diazide 
• 35132-20-8 (R,R)-1,2-diphenylethylenediamine 

Relevant articles and documents

An efficient and practical route to enantiomerically pure (+)-(1R,2R)- and (-)-(1S,2S)-1,2-diphenylethane-1,2-diamines

The synthesis of the title compounds is easily achieved by the asymmetric Sharpless dihydroxylation of trans-stilbene to the corresponding enantiomerically pure diols. The conversion of the diols to the di-p-toluenesulfonates and subsequent reaction with sodium azide affords the diazides, which are reduced by lithium aluminum hydride to the optically pure 1,2-diamines.