1354633-17-2

Basic information

• Product Name: C₁₅H₁₈O₅
• Synonyms: C₁₅H₁₈O₅
• CAS NO: 1354633-17-2
• Molecular Weight: 278.305
• Mol File: 1354633-17-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₅H₁₈O₅(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₅H₁₈O₅(1354633-17-2)
• EPA Substance Registry System: C₁₅H₁₈O₅(1354633-17-2)

Safety Data

• Hazardous Substances Data: 1354633-17-2(Hazardous Substances Data)

Upstream product

• 100126-08-7 3-Brom-4-methoxymethyloxy-phenylessigsaeure-methylester 
• 927-74-2 3-Butyn-1-ol 
• 34918-57-5 methyl 3-bromo-4-hydroxyphenylacetate 
• 14199-15-6 Methyl 4-hydroxyphenylacetate 

Downstream Products

• 1354633-20-7 C₁₃H₁₄O₄ 
• 916243-38-4 methyl 2-{4-[(2-bromobenzyl)oxy]-3-(4-hydroxybut-1-yn-1-yl)phenyl}acetate 
• 1354633-53-6 C₂₀H₂₂O₄ 
• 1354633-50-3 C₂₀H₂₀O₄ 
• 916243-39-5 (Z)-methyl 2-[11-(3-hydroxypropylidene)-6,11-dihydrodibenzo[b,e]oxepin-2-yl]acetate 
• 140462-76-6 olopatadine hydrochloride 

Relevant articles and documents

A new efficient synthetic route for the synthesis of the antiallergic drug, olopatadine hydrochloride, via stereospecific palladium-catalyzed reaction

A new practical and efficient synthetic route for the synthesis of olopatadine hydrochloride via the intramolecular stereospecific seven-membered ring cyclization from an alkyne intermediate using palladium catalyst and hydride source was established. Furthermore, the optimization of that key stereospecific reaction was examined by design of experiment (DoE), and the desired Z-isomer could be obtained with high yield.