13664-14-7

Basic information

• Product Name: Benzamide, 4-fluoro-N-hydroxy-N-phenyl-
• CAS NO: 13664-14-7
• Molecular Formula: C13H10FNO2
• Molecular Weight: 231.226
• Mol File: 13664-14-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Benzamide, 4-fluoro-N-hydroxy-N-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzamide, 4-fluoro-N-hydroxy-N-phenyl-(13664-14-7)
• EPA Substance Registry System: Benzamide, 4-fluoro-N-hydroxy-N-phenyl-(13664-14-7)

Safety Data

• Hazardous Substances Data: 13664-14-7(Hazardous Substances Data)

Upstream product

• 403-43-0 4-fluorobenzoyl chloride 
• 100-65-2 N-Phenylhydroxylamine 
• 459-57-4 4-fluorobenzaldehyde 
• 586-96-9 Nitrosobenzene 
• 98-95-3 nitrobenzene 

Downstream Products

• 456-22-4 4-Fluorobenzoic acid 
• 100-65-2 N-Phenylhydroxylamine 

Relevant articles and documents

Benzaldehyde lyase-catalyzed direct amidation of aldehydes with nitroso compounds

Benzaldehyde lyase from the Pseudomonas fluorescens catalyzes the reaction of aromatic aldehydes with nitroso compounds and furnishes N-arylhydroxamic acids in high yields. Aromatic aldehydes and benzoins are converted into enamine-carbanion-like intermediates prior to their reaction with nitroso compounds. The kinetic resolution of rac-2-hydroxy-1,2-diphenylethanones furnished (S)-benzoins and arylhydroxamic acids with high enantioselectivities and conversions.

Substituent effects in the micellar hydrolysis of N-phenylbenzohydroxamic acid under acidic conditions

The rates of hydrolysis of some para-substituted N-phenylbenzohydroxamic acids (X.C6H4.(C = O).N(OH)C6H5; X = H, CH3, OCH3, F, NO2) under acidic conditions with cationic, anionic and nonionic surfactants have been measured. Substituent effects upon first order rate constants in water and at the micellar surface fitted Hammett equation, based on σ, σ+, σ- parameters. Values of 'p' increase with increasing surfactant concentration. The substituent effects indicate specific micellar influences on the rates and a difference in mechanism between the bulk aqueous phase and the micellar phase. The lipophilicity and polar effects of the substituents have also been evaluated.