137862-40-9Relevant articles and documents
Bisphosphonate prodrugs: Synthesis of new aromatic and aliphatic 1-hydroxy-1,1-bisphosphonate partial esters
Monteil, Maelle,Guenin, Erwann,Migianu, Evelyne,Lutomski, Didier,Lecouvey, Marc
, p. 7528 - 7537 (2005)
Methods for the preparation of various 1-hydroxy-1,1-bisphosphonate partial esters were developed. They were obtained from (alkyl or phenyl) bis(trimethylsilyl) phosphite and aromatic or aliphatic acid chlorides, followed by methanolysis.