138128-01-5Relevant articles and documents
Hydrolysis of nitriles using an immobilized nitrilase: Applications to the synthesis of methionine hydroxy analogue derivatives
Rey, Patrick,Rossi, Jean-Christophe,Taillades, Jacques,Gros, Georges,Nore, Olivier
, p. 8155 - 8162 (2004)
Mild and selective hydrolysis of a large range of nitriles leading to carboxylic acids was achieved under neutral conditions by an immobilized and genetically modified enzyme preparation from Alcaligenes faecalis ATCC8750. This immobilized nitrilase has been shown to be an effective catalyst for the stereoselective hydrolysis of mandelonitrile 1a to R-(-)-mandelic acid 1c. This method is particularly useful for the production of hydroxy analogues of methionine derivatives 2c-4c that could have an interest in cattle feeding and for the transformation of compounds containing other acid- or base-sensitive groups 3a-10a. A series of aliphatic dinitriles 11a-15a was hydrolyzed to the corresponding cyano acids. The suitability of the immobilized catalyst as a robust and versatile biocatalyst is discussed, and models to account for the stereoselectivity of the enzymic hydrolysis have been proposed.
SULFUR-CONTAINING COMPOUNDS AS SOLVENTS
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Page/Page column 42, (2018/03/24)
Methods for using sulfur-containing compounds comprising short chain aliphatic ester or amide moieties as solvents and compositions comprising these compounds are provided.
SULFOXIDE-BASED SURFACTANTS
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Paragraph 0149, (2013/07/19)
The present invention provides sulfoxide compounds comprising hydrophobic ester or amide moieties such that the compounds have surfactant properties. Also provided are methods for using the sulfoxide compounds or mixtures of the sulfoxide compounds in a variety of applications.
