138261-30-0Relevant articles and documents
Synthesis and evaluation of etoposide and podophyllotoxin analogs against topoisomerase IIα and HCT-116 cells
Barton, Christopher E.,Bradley, Amber M.,Deweese, Joseph E.,Kumar, Priyanka,Mercer, Susan L.,Murphy, Matthew B.
, (2020)
Etoposide is a widely-used anticancer agent that targets human type II topoisomerases. Evidence suggests that metabolism of etoposide in myeloid progenitor cells is associated with translocations involved in leukemia development. Previous studies suggest