1676-86-4

Basic information

• Product Name: N6-Carbobenzoxy-L-lysine N-Carboxyanhydride
• Synonyms: N6-Carbobenzoxy-L-lysine N-Carboxyanhydride;(S)-[4-(2,5-Dioxo-4-oxazolidinyl)butyl]carbaMic Acid Phen;L-[4-(2,5-Dioxo-4-oxazolidinyl)butyl]carbaMic Acid Benzyl Ester;Lys(Z)-NCA;N-[(4S)-4-(2,5-Dioxo-4-oxazolidinyl)butyl]carbaMic Acid PhenylMethyl Ester;CarbaMic acid, [4-(2,5-dioxo-4-oxazolidinyl)butyl]-, phenylMethyl ester,(S)-;L-N-Benzoyloxycarbonyl lysine n-carboxyanhydride;L-Lys(Cbz)-NCA
• CAS NO: 1676-86-4
• Molecular Formula: C₁₅H₁₈N₂O₅
• Molecular Weight: 306.31382
• Product Categories: Amino Acids & Derivatives;Aromatics;Chiral Reagents;Heterocycles
• Mol File: 1676-86-4.mol
• Article Data: 72

Chemical Properties

• Appearance: /
• Density: 1.248 g/cm³
• Storage Temp.: 2-8°C
• Solubility: Chloroform (Very Slightly, Sonicated), DMSO (Slightly), Methanol (Slightly)
• PKA: 9.31±0.40(Predicted)
• Stability: Hygroscopic
• CAS DataBase Reference: N6-Carbobenzoxy-L-lysine N-Carboxyanhydride(CAS DataBase Reference)
• NIST Chemistry Reference: N6-Carbobenzoxy-L-lysine N-Carboxyanhydride(1676-86-4)
• EPA Substance Registry System: N6-Carbobenzoxy-L-lysine N-Carboxyanhydride(1676-86-4)

Safety Data

• Hazardous Substances Data: 1676-86-4(Hazardous Substances Data)

Usage

Description

N6-Carbobenzoxy-L-lysine N-Carboxyanhydride is a L-lysine derivative that serves as a key component in the synthesis of Polylysine, a synthetic, basic poly-α-amino acid. N6-Carbobenzoxy-L-lysine N-Carboxyanhydride plays a crucial role in various applications across different industries due to its unique properties and reactivity.

Uses

Used in Pharmaceutical Industry:
N6-Carbobenzoxy-L-lysine N-Carboxyanhydride is used as a building block for the synthesis of Polylysine, which has potential applications in the pharmaceutical industry. Polylysine exhibits antimicrobial properties, making it a valuable compound for developing new drugs to combat infections.
Used in Agriculture:
In the agricultural industry, N6-Carbobenzoxy-L-lysine N-Carboxyanhydride is used as a precursor for Polylysine, which has demonstrated its effectiveness in inhibiting fungal penetration and polyphenol formation in susceptible sweet potatoes infected with C. fimbriata. It also promotes callus formation in resistant sweet potatoes and inhibits the infection of tomato cuttings by F. lycopersici, thus contributing to crop protection and disease management.
Used in Biochemical Research:
N6-Carbobenzoxy-L-lysine N-Carboxyanhydride is utilized as a research tool in biochemical studies. Its role in the synthesis of Polylysine allows scientists to explore the properties and potential applications of this synthetic poly-α-amino acid, furthering our understanding of its biological activities and possible uses in various fields.

Upstream product

• 405-39-0 N,N'-di-[(phenylmethoxy)carbonyl]-L-lysine 
• 1155-64-2 N₆-[(benzyloxy)carbonyl]-L-lysine 
• 75-44-5 phosgene 
• 503-38-8 trichloromethyl chloroformate 
• 32315-10-9 bis(trichloromethyl) carbonate 
• 501-53-1 benzyl chloroformate 
• 56-87-1 L-lysine 
• 116-16-5 1,1,1,3,3,3-hexachloro-propan-2-one 
• 1387552-55-7 C₂₁H₂₄N₂O₆ 
• 32302-83-3 N-ε-benzyloxycarbonyl lysine 
• 657-27-2 L-Lysine hydrochloride 

Downstream Products

• 102495-95-4 N⁶-benzyloxycarbonyl-L-lysine hydrazide 
• 59515-43-4 N^ε-benzyloxycarbonyl-L-lysine ethyl ester hydrochloride 
• 54745-15-2 Nps-Lys(Z)-NCA 
• 116586-26-6 (2S,3aS,7aS)-1-(N⁶-benzyloxycarbonyl-L-lysyl-γ-D-glutamyl)octahydro-1H-indole-2-carboxylic acid 
• 116587-18-9 (2S,3aS,7aS)-1-{(R)-4-[6-Amino-2-(3-cyclohexyl-ureido)-hexanoylamino]-4-carboxy-butyryl}-octahydro-indole-2-carboxylic acid 
• 128595-11-9 (2S,3aS,7aS)-1-{(R)-4-[6-Amino-2-(3-phenyl-propionylamino)-hexanoylamino]-4-carboxy-butyryl}-octahydro-indole-2-carboxylic acid 
• 128595-10-8 (2S,3aS,7aS)-1-(N²-phenylacetyl-L-lysyl-γ-D-glutamyl)octahydro-1H-indole-2-carboxylic acid 
• 116662-73-8 (2S,3aS,7aS)-1-(N²-nicotinoyl-L-lysyl-γ-D-glutamyl)octahydro-1H-indole-2-carboxylic acid 
• 116587-17-8 (2S,3aS,7aS)-1-(N²-benzylcarbamoyl-L-lysyl-γ-D-glutamyl)octahydro-1H-indole-2-carboxylic acid 
• 116587-19-0 (2S,3aS,7aS)-1-{(R)-4-[6-Amino-2-(3-phenyl-ureido)-hexanoylamino]-4-carboxy-butyryl}-octahydro-indole-2-carboxylic acid 
• 116585-98-9 (2S,3aS,7aS)-1-((R)-4-{6-Amino-2-[(biphenyl-4-carbonyl)-amino]-hexanoylamino}-4-carboxy-butyryl)-octahydro-indole-2-carboxylic acid 
• 116586-27-7 (2S,3aS,7aS)-1-(N⁶-Z-N²-nicotinoyl-L-lysyl-γ-D-glutamyl)octahydro-1H-indole-2-carboxylic acid 

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