18297-63-7 Usage
Description
1,3-Bis(trimethylsilyl)urea is a silazane compound, which is an organic derivative of silicon and nitrogen hydrides with a straight or branched chain of silicon and nitrogen atoms joined by covalent bonds. It is structurally analogous to siloxanes, but with -NHgroups replacing the -Ogroups. This white solid with a mild odor is an effective silylating agent and is widely utilized in the pharmaceutical and chemical industries.
Uses
Used in Pharmaceutical Industry:
1,3-Bis(trimethylsilyl)urea is used as a reagent for the silylation of alcohols and carboxylic acids, which is crucial in the synthesis of various pharmaceutical compounds. The silylation process helps protect functional groups during chemical reactions, allowing for selective modifications and enhancing the overall efficiency of the synthesis process.
Used in Chemical Industry:
In the chemical industry, 1,3-Bis(trimethylsilyl)urea serves as a silylating agent for the protection of alcohols and carboxylic acids during chemical reactions. This protection is essential for preventing unwanted side reactions and ensuring the desired product formation. The silylation process also aids in improving the stability and reactivity of the compounds involved in various chemical processes.
Overall, 1,3-Bis(trimethylsilyl)urea plays a significant role in both the pharmaceutical and chemical industries due to its effectiveness as a silylating agent, enabling the selective protection and modification of alcohols and carboxylic acids in various chemical reactions.
Flammability and Explosibility
Notclassified
Check Digit Verification of cas no
The CAS Registry Mumber 18297-63-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,8,2,9 and 7 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 18297-63:
(7*1)+(6*8)+(5*2)+(4*9)+(3*7)+(2*6)+(1*3)=137
137 % 10 = 7
So 18297-63-7 is a valid CAS Registry Number.
InChI:InChI=1/C7H20N2OSi2/c1-11(2,3)9(7(8)10)12(4,5)6/h1-6H3,(H2,8,10)
18297-63-7Relevant articles and documents
Silica Metal Oxide Vesicles Catalyze Comprehensive Prebiotic Chemistry
Mattia Bizzarri, Bruno,Botta, Lorenzo,Pérez-Valverde, Maritza Iveth,Saladino, Raffaele,Di Mauro, Ernesto,García-Ruiz, Juan Manuel
, p. 8126 - 8132 (2018/05/29)
It has recently been demonstrated that mineral self-assembled structures catalyzing prebiotic chemical reactions may form in natural waters derived from serpentinization, a geological process widespread in the early stages of Earth-like planets. We have s
Catalyst for use in production of epoxide, method for producing the catalyst, and method for producing epoxide
-
, (2008/06/13)
To provide an epoxide-production-use catalyst that is suitably used for producing an epoxide by partial oxidation of an unsaturated hydrocarbon, a catalyst in accordance with the present invention is obtained by fixing gold fine particles to a carrier containing an oxide containing at least one of titanium and zirconium, and has an acid quantity of not more than 0.1 mmol/g determined by the NH3-TPD method. Such a catalyst for epoxide producing use can be produced by, for instance, fixing gold fine particles to a carrier having an acid quantity of not more than 0.15 mmol/g. The catalyst for epoxide producing use arranged as above is preferably used as a catalyst in partial oxidation of an unsaturated hydrocarbon to produce a corresponding epoxide.
Catalysts for Silylations with 1,1,1,3,3,3-Hexamethyldisilazane
Bruynes, Cornelis A.,Jurriens, Theodorus K.
, p. 3966 - 3969 (2007/10/02)
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