2065-37-4 Usage
Description
2-Bromo-1,4-naphthoquinone (BrQ) is a 1,4-naphthoquinone derivative that can be prepared by the bromination of 1-naphthol using N-bromosuccinimide. It possesses unique chemical properties and has been evaluated for its efficacy as an antifeedant against the cabbage looper, Trichoplusia ni.
Uses
Used in Chemical Synthesis:
2-Bromo-1,4-naphthoquinone is used as a key intermediate in the preparation of various chemical compounds, including benzo[f]indolequinones, 2-azido-1,4-naphthoquinone, 2-allyl-3-bromo-1,4-naphthoquinone, and 2-(3-indolyl)-1,4-naphthoquinones. These synthesized compounds have potential applications in various fields, such as pharmaceuticals, materials science, and agrochemicals.
Used in Cancer Treatment:
A report suggests that the replacement of 2-methyl-1,4-naphthoquinone with BrQ enhances its ability to produce hydrogen peroxide, which can be employed for cancer treatment. The generation of hydrogen peroxide can induce oxidative stress in cancer cells, leading to cell death and potentially offering a novel therapeutic approach for cancer treatment.
Used in Pest Control:
2-Bromo-1,4-naphthoquinone has been evaluated for its efficacy as an antifeedant against the cabbage looper, Trichoplusia ni. Its use in pest control can help reduce crop damage and contribute to more sustainable agricultural practices.
Check Digit Verification of cas no
The CAS Registry Mumber 2065-37-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,0,6 and 5 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 2065-37:
(6*2)+(5*0)+(4*6)+(3*5)+(2*3)+(1*7)=64
64 % 10 = 4
So 2065-37-4 is a valid CAS Registry Number.
InChI:InChI=1/C10H5BrO2/c11-8-5-9(12)6-3-1-2-4-7(6)10(8)13/h1-5H
2065-37-4Relevant articles and documents
Exploiting photooxygenations mediated by porphyrinoid photocatalysts under continuous flow conditions
De Oliveira, Kleber T.,Miller, L. Zane,McQuade, D. Tyler
, p. 12717 - 12725 (2016/02/12)
Photooxygenation reactions are a powerful synthetic tool to produce oxidized organic compounds; however, these reactions often exhibit experimental limitations including the production of complex mixtures that hinder desired product isolation and scale-up. Herein, we present a photocatalysed protocol under continuous flow conditions using a simple home built photoreactor and porphyrinoids as photocatalysts. Reaction conditions, long-term experiments, and scope demonstrate a protocol that is cost-effective, safe, reproducible and robust, thus allowing the production of relevant substituted naphthoquinones with interest in natural product synthesis and biological activity.
