214360-66-4

Basic information

• Product Name: 4-TERT-BUTYLPHENYLBORONIC ACID, PINACOL ESTER
• Synonyms: 4-TERT-BUTYLPHENYLBORONIC ACID, PINACOL ESTER;2-(4-TERT-BUTYLPHENYL)-4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLANE;4-t-Butylphenylboronic acid,pinacol ester;2-(4-tert-Butylphenyl)-4;2-(tert-Butylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane;4-(tert-Butyl)benzeneboronic acid, pinacol ester
• CAS NO: 214360-66-4
• Molecular Formula: C₁₆H₂₅BO₂
• Molecular Weight: 260.18
• Product Categories: Heterocyclic Compounds
• Mol File: 214360-66-4.mol
• Article Data: 73

Chemical Properties

• Melting Point: 139.9-140.9 °C
• Boiling Point: 333.6°C at 760 mmHg
• Flash Point: 155.5°C
• Appearance: /
• Density: 0.96g/cm³
• Vapor Pressure: 0.000262mmHg at 25°C
• Refractive Index: 1.488
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 4-TERT-BUTYLPHENYLBORONIC ACID, PINACOL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 4-TERT-BUTYLPHENYLBORONIC ACID, PINACOL ESTER(214360-66-4)
• EPA Substance Registry System: 4-TERT-BUTYLPHENYLBORONIC ACID, PINACOL ESTER(214360-66-4)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 214360-66-4(Hazardous Substances Data)

Usage

Uses

4-t-Butylphenylboronic acid, pinacol ester

InChI:InChI=1/C16H25BO2/c1-14(2,3)12-8-10-13(11-9-12)17-18-15(4,5)16(6,7)19-17/h8-11H,1-7H3

Upstream product

• 25240-59-9 pinacolboronic acid 
• 154318-75-9 4-tert-butylphenyl triflate 
• 3972-65-4 1-bromo-4-tert-butylbenzene 
• 61676-62-8 2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 98-54-4 para-tert-butylphenol 
• 76-09-5 2,3-dimethyl-2,3-butane diol 
• 63488-10-8 4-tert-butylmagnesium bromide 
• 123324-71-0 p-tert-butylphenylboronic acid 
• 7598-28-9 4-tert-butylphenyltosylate 
• 73183-34-3 bis(pinacol)diborane 
• 59970-38-6 4-tert-butylphenyl mesylate 
• 3972-56-3 4-(tert-butyl)chlorobenzene 
• 769-92-6 4-tert-Butylaniline 
• 1319748-01-0 1-[2-(4-tert-butylphenyl)diazen-1-yl]pyrrolidine 

Downstream Products

• 3972-65-4 1-bromo-4-tert-butylbenzene 
• 3972-56-3 4-(tert-butyl)chlorobenzene 
• 927811-33-4 bis(4'-tert-butylbiphenylyl)methanone 
• 1174926-56-7 C₅₇H₄₄N₄S₂ 
• 688803-89-6 C₂₆H₂₈N₂S 
• 1152616-36-8 C₂₀H₁₈F₃N₃ 
• 849727-72-6 2-(2-bromo-4-tert-butylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 701-30-4 1-tert-butyl-4-fluorobenzene 
• 1537171-80-4 1-(tert-butyl)-4-(1,1-difluoroallyl)benzene 
• 1537172-04-5 1-(tert-butyl)-4-(3,3-difluoroallyl)benzene 
• 98-54-4 para-tert-butylphenol 
• 329-13-5 1-(1,1-dimethylethyl)-4-(fluoromethyl)benzene 
• 7244-77-1 1-nitro-4-propoxybenzene 
• 231627-97-7 2-(4-(tert-butyl)phenyl)-4H-chromen-4-one 

Relevant articles and documents

Photochemical and electrochemical C-N borylation of arylhydrazines

The C-N borylation of arylhydrazine hydrochlorides with bis(pinacolato)diboron was achieved under photochemical and electrochemical conditions, respectively. This novel and scalable transformation provides two efficient and mild transition-metal-free synt

Remote steric control for undirected meta-selective C-H activation of arenes

Regioselective functionalization of arenes remains a challenging problem in organic synthesis. Steric interactions are often used to block sites adjacent to a given substituent, but they do not distinguish the remaining remote sites. We report a strategy

Carbon-carbon bond activation by B(OMe)3/B2pin2-mediated fragmentation borylation

Selective carbon-carbon bond activation is important in chemical industry and fundamental organic synthesis, but remains challenging. In this study, non-polar unstrained Csp2-Csp3 and Csp2-Csp2 bond activation was achieved by B(OMe)3/B2pin2-mediated fragmentation borylation. Various indole derivatives underwent C2-regioselective C-C bond activation to afford two C-B bonds under transition-metal-free conditions. Preliminary mechanistic investigations suggested that C-B bond formation and C-C bond cleavage probably occurred in a concerted process. This new reaction mode will stimulate the development of reactions based on inert C-C bond activation. This journal is