260391-65-9

Basic information

• Product Name: (2-Amino-4-{3-[5-amino-4-((S)-2-hydroxymethyl-pyrrolidine-1-carbonyl)-2-methoxy-phenoxy]-propoxy}-5-methoxy-phenyl)-((S)-2-hydroxymethyl-pyrrolidin-1-yl)-methanone
• Synonyms: (2-Amino-4-{3-[5-amino-4-((S)-2-hydroxymethyl-pyrrolidine-1-carbonyl)-2-methoxy-phenoxy]-propoxy}-5-methoxy-phenyl)-((S)-2-hydroxymethyl-pyrrolidin-1-yl)-methanone
• CAS NO: 260391-65-9
• Molecular Weight: 572.659
• Mol File: 260391-65-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2-Amino-4-{3-[5-amino-4-((S)-2-hydroxymethyl-pyrrolidine-1-carbonyl)-2-methoxy-phenoxy]-propoxy}-5-methoxy-phenyl)-((S)-2-hydroxymethyl-pyrrolidin-1-yl)-methanone(CAS DataBase Reference)
• NIST Chemistry Reference: (2-Amino-4-{3-[5-amino-4-((S)-2-hydroxymethyl-pyrrolidine-1-carbonyl)-2-methoxy-phenoxy]-propoxy}-5-methoxy-phenyl)-((S)-2-hydroxymethyl-pyrrolidin-1-yl)-methanone(260391-65-9)
• EPA Substance Registry System: (2-Amino-4-{3-[5-amino-4-((S)-2-hydroxymethyl-pyrrolidine-1-carbonyl)-2-methoxy-phenoxy]-propoxy}-5-methoxy-phenyl)-((S)-2-hydroxymethyl-pyrrolidin-1-yl)-methanone(260391-65-9)

Safety Data

• Hazardous Substances Data: 260391-65-9(Hazardous Substances Data)

Upstream product

• 260391-64-8 ((propane-1,3-diylbis(oxy))bis(5-methoxy-2-nitro-4,1-phenylene))bis(((S)-2-(hydroxymethyl)pyrrolidin-1-yl)methanone) 
• 23356-96-9 (S)-1-Pyrrolidin-2-yl-methanol 
• 140658-45-3 1',3'-bis(4-carboxy-2-methoxy-5-nitrophenoxy)propane 

Downstream Products

• 260391-66-0 C₄₅H₅₀N₆O₁₆ 

Relevant articles and documents

Design and synthesis of novel pyrrolobenzodiazepine (PBD) prodrugs for ADEPT and GDEPT

Three N10-(4-nitrobenzyl)carbamate-protected PBD prodrugs (9a, 9b and 15) have been synthesized and evaluated for potential use in nitroreductase-based ADEPT and GDEPT therapies. An approximately 100-fold activation was observed for the DC-81 prodrug 9a.