29934-17-6 Usage
Description
Dichlorobis(tricyclohexylphosphine)palladium(II) is a yellow powder that serves as a catalyst precursor in various carbon-carbon and carbon-heteroatom bond-forming reactions. It is widely used in the field of organic chemistry for its ability to facilitate the formation of new bonds between carbon atoms and other elements, making it a valuable compound for creating complex molecular structures.
Uses
Used in the Chemical Industry:
Dichlorobis(tricyclohexylphosphine)palladium(II) is used as a catalyst for C-C and C-N coupling reactions, which are essential for the synthesis of various organic compounds. Its ability to promote bond formation under mild conditions makes it a preferred choice for many chemical reactions.
Used in the Pharmaceutical Industry:
In the pharmaceutical industry, Dichlorobis(tricyclohexylphosphine)palladium(II) is used as a catalyst in the homogeneous carbonylation of chloroarenes, a process that is crucial for the production of various pharmaceutical compounds.
Used in the Suzuki Reaction:
Dichlorobis(tricyclohexylphosphine)palladium(II) is also used in the Suzuki reaction, a widely employed method for the formation of carbon-carbon bonds. This reaction is particularly useful in the synthesis of complex organic molecules, such as those found in pharmaceuticals and agrochemicals.
Used in Application Guide for Palladium Catalyzed Cross-Coupling Reactions:
As a catalyst precursor, Dichlorobis(tricyclohexylphosphine)palladium(II) is an essential component in the application guide for palladium-catalyzed cross-coupling reactions. These reactions are fundamental in the construction of complex molecular structures and are widely used in the synthesis of various organic compounds, including those with potential applications in materials science, pharmaceuticals, and agrochemicals.
Check Digit Verification of cas no
The CAS Registry Mumber 29934-17-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,9,9,3 and 4 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 29934-17:
(7*2)+(6*9)+(5*9)+(4*3)+(3*4)+(2*1)+(1*7)=146
146 % 10 = 6
So 29934-17-6 is a valid CAS Registry Number.
InChI:InChI=1/2C18H33P.2ClH.Pd/c2*1-4-10-16(11-5-1)19(17-12-6-2-7-13-17)18-14-8-3-9-15-18;;;/h2*16-18H,1-15H2;2*1H;/q;;;;+2/p-2
29934-17-6Relevant articles and documents
A Polystyrene-Cross-Linking Tricyclohexylphosphine: Synthesis, Characterization and Applications to Pd-Catalyzed Cross-Coupling Reactions of Aryl Chlorides
Arashima, Junya,Iwai, Tomohiro,Sawamura, Masaya
supporting information, p. 411 - 415 (2019/02/03)
A polystyrene-cross-linking tricyclohexylphosphine (PS-TCP) was synthesized through radical emulsion polymerization of 4-tert-butylstyrene as a monomer and tris(trans-4-styrylcyclohexyl)phosphine as a threefold cross-linker. The PS-TCP showed enhanced ligand performance compared to the corresponding polystyrene-triphenylphosphine hybrid PS-TPP and tricyclohexylphosphine in Pd-catalyzed Suzuki–Miyaura and Buchwald–Hartwig reactions of aryl chlorides.
Structural studies of PdCl2L2 complexes with fluorinated phosphines, phosphites, and phosphinites as precursors of benzyl bromide carbonylation catalysts, and and X-ray crystal structure of cis-PdCl2[PPh2 (OEt)]2
Trzeciak,Bartosz-Bechowski,Ciunik,Niesyty,Ziolkowski
, p. 752 - 759 (2007/10/03)
PdCl2L2-type complexes with phosphines (L = PPhx(C6F5)3-x (x = 0-3)), phosphites (L = P(OMe)3, P(OPh)3, P(OEt)3), and phosphinites (L = PPh2 (OC6F5), PPh2(O-3,5-F2 C6H3), PPh2(OEt), PPh2 (O-n-Bu), PPh2(O-t-Bu)) were synthesized and characterized by UV-vis and 31P NMR methods. PdCl2L2 complexes with less sterically demanding phosphines (Θ 2[PPh2(OEt)]2. These complexes react with CO in the presence of NEt3 forming Pd(CO)xLy (x + y = 4) type carbonyls characterized by IR spectra. All PdCl2L2 complexes studied are active as precursors of benzyl bromide carbonylation catalysts at 40°C and 1 atm CO; however, the activity of the cis isomers is higher than that of the trans isomers. The highest yields of the carbonylation product, phenylacetic acid methyl ester, were obtained using cis-PdCl2[P(OMe)3]2 (92%), cis-PdCl2[P(OPh)3]2 (89%), and cis-PdCl2[PPh2(O-n-Bu)]2 (78%) as catalyst precursors.
Aktivierung der C-Cl-Bindung: Katalytische Carbonylierung von Dichlormethan und Chlorbenzol
Huser, Marc,Youinou, Marie-Therese,Osborn, John A.
, p. 1427 - 1430 (2007/10/02)
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