369363-23-5

Basic information

• Product Name: Propanedioic acid, [(4-methoxyphenyl)propylamino]-, diethyl ester
• CAS NO: 369363-23-5
• Molecular Formula: C17H25NO5
• Molecular Weight: 323.389
• Mol File: 369363-23-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Propanedioic acid, [(4-methoxyphenyl)propylamino]-, diethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Propanedioic acid, [(4-methoxyphenyl)propylamino]-, diethyl ester(369363-23-5)
• EPA Substance Registry System: Propanedioic acid, [(4-methoxyphenyl)propylamino]-, diethyl ester(369363-23-5)

Safety Data

• Hazardous Substances Data: 369363-23-5(Hazardous Substances Data)

Upstream product

• 609-09-6 Diethyl ketomalonate 
• 104-94-9 4-methoxy-aniline 
• 54723-13-6 2-(4-methoxyphenylimino)malonic acid diethyl ester 
• 927-77-5 n-propylmagnesium bromide 

Downstream Products

• 71193-47-0 N-(4-methoxyphenyl)-N-propylamine 

Relevant articles and documents

Conjugated imines and iminium salts as versatile acceptors of nucleophiles

Growing interests in nitrogen-containing molecules involving bioactive and functional materials have stimulated the recent development of synthetic methodologies where nucleophilic addition reactions to imino carbons are utilized in crucial steps. This article summarizes double nucleophilic addition reactions with α,β-unsaturated aldimines, addition reactions using alkynyl imines, "umpoled" reactions of α-imino esters, and the use of iminium salts as reactive electrophiles. The Royal Society of Chemistry 2009.

Electrophilic amination with iminomalonate

Diethyl N-anisyliminomalonate has been found to be an excellent electrophilic amination reagent for Grignard reagents to give N-alkylated products in good yields, and subsequent air oxidation affords N-alkylanisidines.