41365-75-7 Usage
Description
1-AMINO-3,3-DIETHOXYPROPANE is a clear, colorless to yellow liquid that serves as an effective modulator of alginate and chitosan-based hydrogels. It is widely utilized in various applications across different industries due to its unique properties and versatility.
Uses
Used in Biomedical Applications:
1-AMINO-3,3-DIETHOXYPROPANE is used as a modulator for alginate and chitosan-based hydrogels for the delivery of bone marrow stromal cells (BMSCs) for regeneration of cartilage. Its ability to effectively modulate these hydrogels makes it a valuable component in the field of tissue engineering and regenerative medicine.
Used in Pharmaceutical Industry:
1-AMINO-3,3-DIETHOXYPROPANE is used as a component in the generation of polyethylene glycol (PEG) polyethylenimine (PEI) polyplexes for transfection studies in hepatocellular carcinoma cell cultures. This application highlights its potential in drug delivery systems and gene therapy, contributing to the development of novel treatments for various diseases.
Used in Chemical Synthesis:
1-AMINO-3,3-DIETHOXYPROPANE is used as a component of pH-sensitive PEG derivative for lipopolyplexes formation. This application demonstrates its utility in the development of advanced drug delivery systems, particularly those that are sensitive to changes in pH, allowing for targeted and controlled release of therapeutic agents.
Used in Material Science:
1-AMINO-3,3-DIETHOXYPROPANE is used with alginate in the preparation of hydrogels. These hydrogels have a wide range of applications in material science, including tissue engineering, drug delivery, and as scaffolds for cell growth. The incorporation of 1-AMINO-3,3-DIETHOXYPROPANE enhances the properties of these hydrogels, making them more suitable for their intended applications.
Check Digit Verification of cas no
The CAS Registry Mumber 41365-75-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,1,3,6 and 5 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 41365-75:
(7*4)+(6*1)+(5*3)+(4*6)+(3*5)+(2*7)+(1*5)=107
107 % 10 = 7
So 41365-75-7 is a valid CAS Registry Number.
InChI:InChI=1/C7H17NO2/c1-3-9-7(5-6-8)10-4-2/h7H,3-6,8H2,1-2H3/p+1
41365-75-7Relevant articles and documents
Synthetic studies on statins. Part 1: A short and cyanide-free synthesis of atorvastatin calcium via an enantioselective aldol strategy
Hu, Lemeng,Xiong, Fangjun,Chen, Xiaofei,Chen, Wenxue,He, Qiuqin,Chen, Fener
, p. 207 - 211 (2013/04/10)
A short and cyanide-free enantioselective synthesis of atorvastatin calcium has been achieved starting from a commercially available highly substituted 1,4-diketone in an overall yield of 40%. The key step in this approach is the asymmetric aldol reaction of an aldehyde with diketene in the presence of Ti(O-i-Pr)4-Schiff base complex to create the (5R)-stereochemistry of atorvastatin calcium.
Bifunctional polyethylene glycol derivatives
-
, (2008/06/13)
The present invention provides novel heterobifunctional and monobifunctional polyethylene glycol derivatives for the pegylation of therapeutically active proteins. The heterobifunctional PEGs which bear two different functional groups as well as the monobifunctional PEGs which contain two similar functional groups, may be used for cross-linking purposes. The cross-linking may be intramolecular between two areas within the same molecule or intermolecular between two separate molecules. The pegylated protein conjugates that are produced, retain a substantial portion of their therapeutic activity and are less immunogenic than the protein from which the conjugate is derived. New syntheses for preparing such bifunctional derivatives are described.
Tricyclic benzomorphan analogues by intramolecular Oxa-Pictet-Spengler reaction
Wunsch,Zott
, p. 2307 - 2310 (2007/10/02)
The key step in the regio- and stereoselective preparation of the benzomorphan analogues 9, 10a, 10b, 14 and 15 is an intramolecular Oxa-Pictet-Spengler reaction. Masked as an acetal the carbonyl component is connected via an amide to the 2-phenylethanol component (7, 12).