51721-35-8

Basic information

• Product Name: 3-Hexyn-1-ol, 4-methylbenzenesulfonate
• CAS NO: 51721-35-8
• Molecular Formula: C13H16O3S
• Molecular Weight: 252.334
• Mol File: 51721-35-8.mol
• Article Data: 13

Chemical Properties

• CAS DataBase Reference: 3-Hexyn-1-ol, 4-methylbenzenesulfonate(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Hexyn-1-ol, 4-methylbenzenesulfonate(51721-35-8)
• EPA Substance Registry System: 3-Hexyn-1-ol, 4-methylbenzenesulfonate(51721-35-8)

Safety Data

• Hazardous Substances Data: 51721-35-8(Hazardous Substances Data)

Upstream product

• 1002-28-4 3-hexyn-1-ol 
• 98-59-9 p-toluenesulfonyl chloride 
• 598-23-2 3-methyl-but-1-yne 
• 98-68-0 4-methoxy-phenyl-sulphonyl chloride 
• 15787-92-5 4-methyl-2-pentyn-1-ol 

Downstream Products

• 35545-23-4 1-bromo-hex-3-yne 
• 1041847-83-9 [NMe₂(4-methyl-2-pentynyl)(CH=C(CH₃)2)][OTS] 
• 1001289-70-8 3-(hex-3-ynyloxy)-4-methoxybenzaldehyde 
• 1001289-68-4 4-(hex-3-ynyloxy)-3-methoxybenzaldehyde 

Relevant articles and documents

COMPOUNDS HAVING AGONISTIC EFFECT AGAINST GPR84, PREPARATION METHOD FOR COMPOUNDS AND USE OF COMPOUNDS

The present invention relates to a class of compounds represented by the formula I, or pharmaceutically acceptable salts thereof, methods for their preparation, and application as small molecule tools that function as GPR84 agonists, and their use in preparing a medicament for the treatment of septicemia.

Regioselective Amine–Borane Cyclization: Towards the Synthesis of 1,2-BN-3-Cyclohexene by Copper-Assisted Triazole/Gold Catalysis

The combination of triazole/gold (TA-Au) and Cu(OTf)2is identified as the optimal catalytic system for promoting intramolecular hydroboration for the synthesis of a six-membered cyclic amine–borane. Excellent yields (up to 95 %) and regioselectivities (5-exo vs. 6-endo) were achieved through catalyst control and sequential dilution. Good functional-group tolerance was attained, thus allowing the preparation of highly functionalized cyclic amine–borane substrates, which could not be achieved using other methods. Deuterium-labeling studies support the involvement of a hydride addition to a gold-activated alkyne with subsequent C?B bond formation.

ITRACONAZOLE ANALOGS AND USE THEREOF

Provided herein are Itraconazole analogs. Also provided herein are methods of inhibition of Hedgehog pathway, vascular endothelial growth factor receptor 2 (VEGFR2) glycosylation, angiogenesis and treatment of disease with Itraconazole analogs.