63914-07-8

Basic information

• Product Name: Thymidine, 3'-(4-methylbenzenesulfonate)
• CAS NO: 63914-07-8
• Molecular Formula: C17H20N2O7S
• Molecular Weight: 396.421
• Mol File: 63914-07-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Thymidine, 3'-(4-methylbenzenesulfonate)(CAS DataBase Reference)
• NIST Chemistry Reference: Thymidine, 3'-(4-methylbenzenesulfonate)(63914-07-8)
• EPA Substance Registry System: Thymidine, 3'-(4-methylbenzenesulfonate)(63914-07-8)

Safety Data

• Hazardous Substances Data: 63914-07-8(Hazardous Substances Data)

Upstream product

• 21090-30-2 3'-O-acetylthymidine 
• 98-59-9 p-toluenesulfonyl chloride 
• 50-89-5 thymidine 
• 40615-39-2 5'-O-(4-4'-dimethoxytrityl)thymidine 

Downstream Products

• 3458-14-8 5'-deoxythymidine 
• 15425-09-9 3,5'-cyclo-2'-deoxyguanosine 

Relevant articles and documents

A convenient method for the conversion of β-thymidine to α-thymidine based on TMSOTf-mediated C1′-epimerization

A practically useful method for the synthesis of α-thymidine from β-thymidine was developed by trimethylsilyl triflate-mediated C1′-epimerization. When 5′-O-diphenylacetyl-3′-O-toluoylthymidine was trimethylsilylated and successively treated with TMSOTf in acetonitrile, the resulting α-thymidine derivative was crystallized and isolated without silica-gel column chromatography. Deprotection gave unprotected α-thymidine in an overall yield of 50% from β-thymidine.