6520-83-8

Basic information

• Product Name: 2-METHOXY-6-METHYLBENZOIC ACID ETHYL ESTER
• Synonyms: ETHYL 2-METHOXY-6-METHYLBENZOATE;2-METHOXY-6-METHYLBENZOIC ACID ETHYL ESTER;Methoxymethylbenzoicacidethylester;2-Methyl-6-methoxybenzoic acid ethyl ester;2-Methoxy-6-methylbenzoic acid ethyl ester ,95%
• CAS NO: 6520-83-8
• Molecular Formula: C₁₁H₁₄O₃
• Molecular Weight: 194.23
• Mol File: 6520-83-8.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 135 °C / 15mmHg
• Flash Point: 109.643 °C
• Appearance: /
• Density: 1,09 g/cm3
• Vapor Pressure: 0.006mmHg at 25°C
• Refractive Index: 1.5100 to 1.5130
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 2-METHOXY-6-METHYLBENZOIC ACID ETHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 2-METHOXY-6-METHYLBENZOIC ACID ETHYL ESTER(6520-83-8)
• EPA Substance Registry System: 2-METHOXY-6-METHYLBENZOIC ACID ETHYL ESTER(6520-83-8)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 6520-83-8(Hazardous Substances Data)

Usage

General Description

2-Methoxy-6-methylbenzoic acid ethyl ester, also known as ethyl 2-methoxy-6-methylbenzoate, is an organic compound used in the production of fragrances and flavorings. It is a clear, colorless liquid with a sweet, fruity odor. This chemical is commonly found in cosmetics, soaps, and other personal care products as a fragrance ingredient. It is also used as a flavoring agent in food products. Additionally, 2-methoxy-6-methylbenzoic acid ethyl ester is utilized in the manufacturing of pharmaceuticals and as a solvent in various industrial processes. However, it should be handled with caution as it may cause skin and eye irritation and is flammable.

InChI:InChI=1/C11H14O3/c1-4-14-11(12)10-8(2)6-5-7-9(10)13-3/h5-7H,4H2,1-3H3

Upstream product

• 6555-40-4 ethyl 2-hydroxy-6-methylbenzoate 
• 74-88-4 methyl iodide 
• 77-78-1 dimethyl sulfate 

Downstream Products

• 109480-76-4 2-Methoxy-6-(2-oxo-2-phenyl-ethyl)-benzoic acid ethyl ester 
• 100948-56-9 2-Methanesulfinyl-1-(2-methoxy-6-methyl-phenyl)-ethanone 
• 73318-21-5 2-Methoxy-6-phenylsulfanylmethyl-benzoic acid ethyl ester 
• 73318-24-8 2-(Bis-phenylsulfanyl-methyl)-6-methoxy-benzoic acid ethyl ester 
• 188579-49-9 ethyl 2-methoxy-6-(pentadeca-8,11-diynyl)benzoate 
• 186670-55-3 ethyl 6-(11-dodecenyl)-2-methoxybenzoate 
• 114802-12-9 ethyl 2-methoxy-6-[8(Z)-pentadecenyl]benzoate 
• 186670-45-1 2-ethyl-6-methoxybenzoic acid ethyl ester 
• 808127-81-3 4-bromo-7-hydroxy-2,3-dihydro-1H-isoindol-1-one 
• 1033809-85-6 7-hydroxy-2,3-dihydro-1H-isoindol-1-one 
• 1033809-86-7 7-(2-chloro-4-nitrophenoxy)-2,3-dihydro-1H-isoindol-1-one 
• 1033809-87-8 7-(4-amino-2-chlorophenoxy)-2,3-dihydro-1H-isoindol-1-one 
• 133379-06-3 ethyl 2-methoxy-5-bromo-6-methylbenzoate 
• 73713-37-8 2-Dibromomethyl-6-methoxy-benzoic acid ethyl ester 

Relevant articles and documents

Imidazo[1,2-a]pyridine derivatives, methods of preparing the same and use thereof

The present invention relates to an imidazo[1,2-a]pyridine derivative, and more specifically, to an imidazo[1,2-a]pyridine derivative having excellent gastric acid secretion inhibitory activity, a method of preparing the same, and a use thereof. The imidazo[1,2-a]pyridine derivative according to the present invention has gastric acid secretion inhibitory activity, and can be usefully applied for preventing or treating gastrointestinal inflammatory diseases or gastric-related diseases.(AA) Control group(BB) Example 6(CC) Example 7(DD) Embodiment 11COPYRIGHT KIPO 2017

Efficient total synthesis of AI-77-B, a gastroprotective substance from Bacillus pumilus AI-77

First total synthesis of AI-77-B (1), a gastroprotective substance from Bacillus pumilus AI-77, was achieved in a stereoselective and convergent manner. In this synthesis, the dihydroisocoumarin part 2 was constructed in one step through 1,2-addition of the benzylic anion 17b to Boc-L-leucinal 7b. The hydroxy amino acid 4 was elaborated from (R)-glutamic acid in a highly stereoselective manner. Condensation of 2·HCl and 4, intramolecular Pinner reaction, followed by mild hydrolysis afforded AI-77-B (1).

Synthesis of Gerberinol-I

The synthesis of 4-hydroxy-5-methylcoumarin (II) is described.The compound (II) affords gerberinol-I (I) on treatment with formaldehyde.The synthetic sample of I is identical (m.m.p. and co-IR) with an authentic I.