69813-77-0

Basic information

• Product Name: 2-(4-nitro-phenyl)-2-hydroxypropanenitrile
• Synonyms: 2-(4-nitro-phenyl)-2-hydroxypropanenitrile
• CAS NO: 69813-77-0
• Molecular Weight: 192.174
• Mol File: 69813-77-0.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 2-(4-nitro-phenyl)-2-hydroxypropanenitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-nitro-phenyl)-2-hydroxypropanenitrile(69813-77-0)
• EPA Substance Registry System: 2-(4-nitro-phenyl)-2-hydroxypropanenitrile(69813-77-0)

Safety Data

• Hazardous Substances Data: 69813-77-0(Hazardous Substances Data)

Upstream product

• 7677-24-9 trimethylsilyl cyanide 
• 100-19-6 (4-nitrophenyl)ethanone 
• 151-50-8 potassium cyanide 

Downstream Products

• 81168-94-7 2-hydroxy-2-(4-nitrophenyl)propionic acid 
• 129602-98-8 2-(4-aminophenyl)propanoic acid hydrochloride 
• 131131-34-5 ZM 147376 
• 81168-91-4 2-acetoxy-2-(4-nitrophenyl)propionic acid 
• 82026-80-0 Methanesulfonic acid cyano-methyl-(4-nitro-phenyl)-methyl ester 

Relevant articles and documents

Novel uncatalyzed hydrocyanation of ketones utlizing tetrachlorosilane- potassium cyanide reagent

A combination of tetrachlorosilane and potassium cyanide (in situ trichlorosilyl cyanide) was found to work efficiently for hydrocyanation of ketones to afford the corresponding cyanohydrins in high yield under mild conditions. Copyright Taylor & Francis Group, LLC.

TYK2 INHIBITORS AND USES THEREOF

The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of TYK2, and the treatment of TYK2-mediated disorders.

Conversion of ketones to cyanohydrins: Benzophenone cyanohydrin

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