7007-32-1Relevant articles and documents
Ultrafast Photoclick Reaction for Selective18F-Positron Emission Tomography Tracer Synthesis in Flow
Fu, Youxin,Helbert, Hugo,Simeth, Nadja A.,Crespi, Stefano,Spoelstra, Gerbren B.,van Dijl, Jan Maarten,van Oosten, Marleen,Nazario, Luiza Reali,van der Born, Dion,Luurtsema, Gert,Szymanski, Wiktor,Elsinga, Philip H.,Feringa, Ben L.
supporting information, p. 10041 - 10047 (2021/07/21)
The development of very fast, clean, and selective methods for indirect labeling in PET tracer synthesis is an ongoing challenge. Here we present the development of an ultrafast photoclick method for the synthesis of short-lived18F-PET tracers
BIPHENYL COMPOUNDS AND USES THEREOF
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Paragraph 00234, (2015/05/19)
The present invention relates to biphenyl compounds and uses thereof in medicine. Specifically, the present invention relates to a compound of Formula (I), or a stereoisomer, a geometric isomer, a tautomer, a mesomer, a racemate, an enantiomer, a diastereoisomer, an N-oxide, a hydrate, a solvate, a metabolite, a hydrolysate, a pharmaceutically acceptable salt or a prodrug thereof. The compound disclosed herein is used as a therapeutic agent particularly a GPR40 agonist for treating diabetes and metabolic disease in a patient.
On the Mechanism of Organoaluminum-Promoted Claisen Rearrangement of Allylic Vinyl Ethers
Nonoshita, Katsumasa,Maruoka, Keiji,Yamamoto, Hisashi
, p. 541 - 545 (2007/10/02)
The organoaluminum-promoted Claisen rearrangement of allylic vinyl ethers has been mechanistically studied by two sets of experiments and the observed Z and E selectivity is best accounted for by two possible chair-like structures with R substituents axial and equatorial, respectively.