7257-94-5Relevant articles and documents
Novel preparation and reactivity of poly[4-hydroxy(tosyloxy)iodo]styrenes
Abe,Sakuratani,Togo
, p. 22 - 24 (2001)
Poly[4-hydroxy(tosyloxy)iodo]styrene (high M.W.) and poly{α-methyl[4-hydroxy(tosyloxy)iodo]styrene} (low M.W.) were prepared from polystyrene (average M.W. = 45,000) and poly(α-methylstyrene) (average M.W. = 6,200), respectively, and their reactivities fo
Iridium(III)-Catalyzed Tandem Annulation of Pyridine-Substituted Anilines and α-Cl Ketones for Obtaining 2-Arylindoles
Cui, Xin-Feng,Qiao, Xin,Wang, He-Song,Huang, Guo-Sheng
, p. 13517 - 13528 (2020/12/15)
A facile and expeditious protocol for the synthesis of 2-arylindole compounds from readily available N-(2-pyridyl)anilines and commercially available α-Cl ketones through iridium-catalyzed C-H activation and cyclization is reported here. As a complementary approach to the conventional strategies for indole synthesis, the transformation exhibits powerful reactivity, tolerates a large number of functional groups, and proceeds with good to excellent yields under mild conditions, providing a straightforward method to obtain structurally diverse and valuable indole scaffolds. Furthermore, the reaction could be easily scaled up to gram scale.
Regioselective three-component synthesis of 1,2-diarylindoles from cyclohexanones, α-hydroxyketones and anilines under transition-metal-free conditions
Li, Cheng,Xie, Yanjun,Xiao, Fuhong,Huang, Huawen,Deng, Guo-Jun
supporting information, p. 4079 - 4082 (2019/04/25)
A facile method for the one-pot synthesis of 1,2-diarylindoles under transition-metal-free conditions is described. Cyclohexanones were used as the aryl sources via the dehydrogenative aromatization process. One C-C and two C-N bonds were selectively formed via a domino reaction. This protocol provides a convenient approach for the construction of valuable bioactive 1,2-diarylindoles from readily available cyclohexanones, α-hydroxyketones and anilines.