736-31-2

Basic information

• Product Name: (E)-1,1′-(1,2-ETHENEDIYL)BIS(4-NITROBENZENE)
• Synonyms: Ccris 8546;Einecs 212-002-0;(E)-p,p'-Dinitrostilbene;(E)-4,4'-Dinitrostilbene;Stilbene, 4,4'-dinitro-, (E)-;1,1'-(E)-ethene-1,2-diylbis(4-nitrobenzene);(E)-1,1'-(1,2-Ethenediyl)bis(4-nitrobenzene);1,1'-[(E)-1,2-Ethenediyl]bis(4-nitrobenzene);Benzene, 1,1'-(1E)-1,2-ethenediylbis[4-nitro-;1-nitro-4-[(E)-2-(4-nitrophenyl)ethenyl]benzene
• CAS NO: 736-31-2
• Molecular Formula: C₁₄H₁₀N₂O₄
• Molecular Weight: 270.24
• EINECS: 212-002-0
• Mol File: 736-31-2.mol
• Article Data: 66

Chemical Properties

• Melting Point: 288 °C
• Boiling Point: 394.6°Cat760mmHg
• Flash Point: 182.7°C
• Appearance: /
• Density: 1.376g/cm³
• Refractive Index: 1.6500 (estimate)
• CAS DataBase Reference: (E)-1,1′-(1,2-ETHENEDIYL)BIS(4-NITROBENZENE) (CAS DataBase Reference)
• NIST Chemistry Reference: (E)-1,1′-(1,2-ETHENEDIYL)BIS(4-NITROBENZENE) (736-31-2)
• EPA Substance Registry System: (E)-1,1′-(1,2-ETHENEDIYL)BIS(4-NITROBENZENE) (736-31-2)

Safety Data

• Hazardous Substances Data: 736-31-2(Hazardous Substances Data)

Usage

Description

(E)-1,1'-(1,2-ETHENEDIYL)BIS(4-NITROBENZENE), also known as 1,2-bis(4-nitrophenyl)ethene, is a chemical compound with the molecular formula C14H10N4O4. It is a yellow crystalline solid that is insoluble in water but soluble in organic solvents. (E)-1,1′-(1,2-ETHENEDIYL)BIS(4-NITROBENZENE) is known for its potential applications in various fields, including organic synthesis, pharmaceuticals, and agrochemicals.

Uses

Used in Organic Synthesis:
(E)-1,1'-(1,2-ETHENEDIYL)BIS(4-NITROBENZENE) is used as an intermediate in the synthesis of various organic compounds and dyes. Its unique structure allows it to be a valuable building block for creating a wide range of chemical products.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, (E)-1,1'-(1,2-ETHENEDIYL)BIS(4-NITROBENZENE) is used as a key component in the production of certain drugs. Its properties make it suitable for the development of new pharmaceuticals with potential therapeutic applications.
Used in Agrochemical Industry:
(E)-1,1'-(1,2-ETHENEDIYL)BIS(4-NITROBENZENE) also finds application in the agrochemical industry, where it is utilized in the development of pesticides and other agricultural chemicals. Its chemical properties contribute to the effectiveness of these products in protecting crops and enhancing agricultural productivity.
Used in Materials Science:
(E)-1,1'-(1,2-ETHENEDIYL)BIS(4-NITROBENZENE) may have potential applications in the field of materials science, particularly in the development of new functional materials. Its unique properties could be harnessed to create innovative materials with specific characteristics for various applications.
Safety Precautions:
It is important to handle (E)-1,1'-(1,2-ETHENEDIYL)BIS(4-NITROBENZENE) with care, as it is toxic and can cause irritation to the skin, eyes, and respiratory system. Proper safety measures, including the use of personal protective equipment and proper ventilation, should be taken to minimize the risk of exposure.

Upstream product

• 122-04-3 4-nitro-benzoyl chloride 
• 570-08-1 diethyl acetylmalonate 
• 141-52-6 sodium ethanolate 
• 100-14-1 4-nitrobenzyl chloride 
• 74-85-1 ethene 
• 121986-07-0 p-nitromandelonitrile 
• 1530-42-3 (4-nitrobenzyl)triphenylphosphonium chloride 
• 3145-86-6 4-nitrobenzyl iodide 
• 882-06-4 4-nitro-trans-cinnamic acid 
• 100-01-6 4-nitro-aniline 
• 736-30-1 1,2-bis(4-nitrophenyl)ethane 
• 99-99-0 1-methyl-4-nitrobenzene 
• 2609-49-6 diethyl p-nitrobenzylphosphonate 
• 555-16-8 4-nitrobenzaldehdye 

Downstream Products

• 619-93-2 (Z)-4,4'-dinitrostilbene 
• 105222-70-6 α,α'-dichloro-4,4'-dinitro-bibenzyl 
• 93968-39-9 meso-1,2-dibromo-1,2-di(4-nitrophenyl)-2-ethane 
• 13190-56-2 4,4'-ethanediyl-bis-cyclohexylamine 
• 7314-06-9 (E)-4,4'-diaminostilbene 
• 7297-52-1 nitroaminostilbene 
• 1075218-61-9 N-methyl-{4-[2-(4-amino-phenyl)-vinyl]-phenyl}-amine 
• 621-95-4 4,4'-diaminodihydrostilbene 
• 1609430-93-4 (1S,2S)-1,2-bis(4-nitrophenyl)ethane-1,2-diol 
• 62-23-7 4-nitro-benzoic acid 
• 659-22-3 4,4'-dihydroxystilbene 
• 59857-45-3 4.4'-bis-benzamino-trans-stilbene 
• 81349-03-3 4.4'-bis-benzamino-cis-stilbene 
• 34321-29-4 cis-stilbene-4,4'-diyldiamine 

Relevant articles and documents

Effect of the Linking Group on the Thermoelectric Properties of Poly(Schiff Base)s and Their Metallopolymers

As polymer-based thermoelectric (TE) materials possess attractive features such as light weight, flexibility, low toxicity and ease of processibility, an increasing number of conducting polymers and their composites with high TE performances have been developed in recent years. Up to date, however, the research focusing on the structure-performance relationship remains rare. In this paper, two series of poly(Schiff base)s with either C=C or C≡C linker and their metallopolymers were synthesized and doped with single-walled carbon nanotubes to evaluate how the linking groups affected the TE properties of the resulting composites. Apart from the effect exerted by the morphology, experimental results suggested that the linkers played a key role in determining the band gaps, preferred molecular conformation and extent of conjugation of the polymers, which became key factors that influenced the TE properties of the resulting materials. Additionally, upon coordination with transition metal ions, the TE properties could be tuned readily.

Second-generation aryl isonitrile compounds targeting multidrug-resistant Staphylococcus aureus

Antibiotic resistance remains a major global public health threat that requires sustained discovery of novel antibacterial agents with unexploited scaffolds. Structure-activity relationship of the first-generation aryl isonitrile compounds we synthesized led to an initial lead molecule that informed the synthesis of a second-generation of aryl isonitriles. From this new series of 20 compounds, three analogues inhibited growth of methicillin-resistant Staphylococcus aureus (MRSA) (from 1 to 4 μM) and were safe to human keratinocytes. Compound 19, with an additional isonitrile group exhibited improved activity against MRSA compared to the first-generation lead compound. This compound emerged as a candidate worthy of further investigation and further reinforced the importance of the isonitrile functionality in the compounds’ anti-MRSA activity. In a murine skin wound model, 19 significantly reduced the burden of MRSA, similar to the antibiotic fusidic acid. In summary, 19 was identified as a new lead aryl isonitrile compound effective against MRSA.