858676-94-5

Basic information

• Product Name: {6-[6-(6-{6-[4-(4-methoxy-benzyloxy)-3,5-dimethyl-hex-1-enyl]-2-phenyl-[1,3]dioxan-4-ylmethyl}-2-phenyl-[1,3]dioxan-4-ylmethyl)-2,2-dimethyl-[1,3]dioxan-4-ylmethyl]-2-phenyl-[1,3]dioxan-4-yl}-acetaldehyde
• Synonyms: {6-[6-(6-{6-[4-(4-methoxy-benzyloxy)-3,5-dimethyl-hex-1-enyl]-2-phenyl-[1,3]dioxan-4-ylmethyl}-2-phenyl-[1,3]dioxan-4-ylmethyl)-2,2-dimethyl-[1,3]dioxan-4-ylmethyl]-2-phenyl-[1,3]dioxan-4-yl}-acetaldehyde
• CAS NO: 858676-94-5
• Molecular Weight: 933.192
• Mol File: 858676-94-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: {6-[6-(6-{6-[4-(4-methoxy-benzyloxy)-3,5-dimethyl-hex-1-enyl]-2-phenyl-[1,3]dioxan-4-ylmethyl}-2-phenyl-[1,3]dioxan-4-ylmethyl)-2,2-dimethyl-[1,3]dioxan-4-ylmethyl]-2-phenyl-[1,3]dioxan-4-yl}-acetaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: {6-[6-(6-{6-[4-(4-methoxy-benzyloxy)-3,5-dimethyl-hex-1-enyl]-2-phenyl-[1,3]dioxan-4-ylmethyl}-2-phenyl-[1,3]dioxan-4-ylmethyl)-2,2-dimethyl-[1,3]dioxan-4-ylmethyl]-2-phenyl-[1,3]dioxan-4-yl}-acetaldehyde(858676-94-5)
• EPA Substance Registry System: {6-[6-(6-{6-[4-(4-methoxy-benzyloxy)-3,5-dimethyl-hex-1-enyl]-2-phenyl-[1,3]dioxan-4-ylmethyl}-2-phenyl-[1,3]dioxan-4-ylmethyl)-2,2-dimethyl-[1,3]dioxan-4-ylmethyl]-2-phenyl-[1,3]dioxan-4-yl}-acetaldehyde(858676-94-5)

Safety Data

• Hazardous Substances Data: 858676-94-5(Hazardous Substances Data)

Upstream product

• 77-76-9 2,2-dimethoxy-propane 
• 858676-92-3 benzyl-(2-{6-[6-(6-{6-[4-(4-methoxy-benzyloxy)-3,5-dimethyl-hex-1-enyl]-2-phenyl-[1,3]dioxan-4-ylmethyl}-2-phenyl-[1,3]dioxan-4-ylmethyl)-2,2-dimethyl-[1,3]dioxan-4-ylmethyl]-2-phenyl-[1,3]dioxan-4-yl}-vinyl)-dimethyl-silane 

Downstream Products

• 858676-73-0 2-((2R,4R,6S)-6-(((4S,6S)-6-(((2R,4R,6S)-6-(((2R,4R,6R)-6-((E,3S,4S)-4-hydroxy-3,5-dimethylhex-1-enyl)-2-phenyl-1,3-dioxan-4-yl)methyl)-2-phenyl-1,3-dioxan-4-yl)methyl)-2,2-dimethyl-1,3-dioxan-4-yl)methyl)-2-phenyl-1,3-dioxan-4-yl)acetaldehyde 
• 858676-96-7 C₅₉H₇₂O₁₀ 
• 154396-73-3 RK-397 

Relevant articles and documents

Total synthesis of RK-397

An enantioselective synthesis of the polyene macrolide RK-397 is described. The use of the same eight-carbon building block twice for the construction of the polyol chain allowed for a highly convergent synthesis. The synthesis highlights stereoselective vinylogous aldol addition using a chiral bisphosphoramide as well as a sequential palladium-catalyzed cross-coupling reaction for the preparation of key fragments. Copyright