86031-24-5 Usage
Description
Hydroxylamine, O-[(1,1-dimethylethoxy)carbonyl]-, is a chemical compound that serves as a versatile reactant in various chemical reactions and processes. It is characterized by its ability to form stable carbamates and is commonly used in the modification and functionalization of proteins.
Uses
Used in Biochemistry and Molecular Biology:
Hydroxylamine, O-[(1,1-dimethylethoxy)carbonyl]-, is used as a reactant in the PEGylation and dimerization of expressed proteins. This process allows for the attachment of polyethylene glycol (PEG) chains to proteins, enhancing their stability, solubility, and circulation time in biological systems. PEGylation is particularly useful in the development of therapeutic proteins and drug delivery systems, as it can improve their pharmacokinetic properties and reduce immunogenicity.
Additionally, the compound can be employed in the dimerization of proteins, which may be useful for studying protein-protein interactions, developing novel biomaterials, or creating artificial enzymes with enhanced catalytic properties.
Check Digit Verification of cas no
The CAS Registry Mumber 86031-24-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,6,0,3 and 1 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 86031-24:
(7*8)+(6*6)+(5*0)+(4*3)+(3*1)+(2*2)+(1*4)=115
115 % 10 = 5
So 86031-24-5 is a valid CAS Registry Number.
86031-24-5Relevant articles and documents
SYNTHESIS OF tert-BUTYL AMINOCARBONATE, A NEW TYPE OF COMPOUND THAT CAN BE USED TO ACYLATE AMINES
Harris, Robert B.,Wilson, Irwin B.
, p. 231 - 232 (1983)
tert-Butyl aminocarbonate (tert-butyloxycarbonyloxyamine) was prepared by reaction of hydroxylamine with excess di-tert-butyl dicarbonate.Amino carbonates have not previously been described.This compound rapidly acylates amines in both organic and aqueous solutions.
Sodium channel drugs and uses
-
, (2008/06/13)
The compounds of this invention comprise 2-10 ligands covalently connected, each of the ligands being capable of binding to a ligand binding site in a Na+channel, thereby modulating the biological activities thereof.