86217-82-5

Basic information

• Product Name: 1-BIPHENYL-4-YL-ETHYLAMINE
• Synonyms: CHEMBRDG-BB 4102675;1-BIPHENYL-4-YL-ETHYLAMINE;4-(1-Aminoethyl)biphenyl;(1-biphenyl-4-ylethyl)amine(SALTDATA: HCl);1-(4-Biphenylyl)ethylaMine, 97%;1-(4-Biphenyl)ethylamine;[1,1'-Biphenyl]-4-methanamine, .alpha.-methyl-;1-(4-phenylphenyl)ethanamine hydrochloride
• CAS NO: 86217-82-5
• Molecular Formula: C₁₄H₁₅N
• Molecular Weight: 197.28
• Mol File: 86217-82-5.mol
• Article Data: 18

Chemical Properties

• Boiling Point: 327.5°C at 760 mmHg
• Flash Point: 156°C
• Appearance: /
• Density: 1.027g/cm³
• Vapor Pressure: 0.000201mmHg at 25°C
• Refractive Index: 1.58
• CAS DataBase Reference: 1-BIPHENYL-4-YL-ETHYLAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-BIPHENYL-4-YL-ETHYLAMINE(86217-82-5)
• EPA Substance Registry System: 1-BIPHENYL-4-YL-ETHYLAMINE(86217-82-5)

Safety Data

• Hazard Codes: Xi,N,Xn
• Statements: 22-50
• Safety Statements: 61
• HazardClass: IRRITANT
• Hazardous Substances Data: 86217-82-5(Hazardous Substances Data)

Usage

InChI:InChI=1/C14H15N/c1-11(15)12-7-9-14(10-8-12)13-5-3-2-4-6-13/h2-11H,15H2,1H3

Upstream product

• 92-91-1 biphenyl-4-acetaldehyde 
• 77287-34-4 formamide 
• 99-90-1 para-bromoacetophenone 
• 98-80-6 phenylboronic acid 
• 35588-60-4 p-chloro-(R,S)-1-phenylethylamine 
• 24358-62-1 1-(4-bromophenyl)ethylamine 
• 75408-89-8 4-acetylbiphenyl oxime 
• 540-69-2 ammonium formate 

Downstream Products

• 71350-68-0 2-Amino-1-biphenyl-4-yl-ethanone; hydrochloride 
• 86217-82-5 (+)-1-biphenyl-4-yl-ethylamine 
• 86217-82-5 (-)-1-biphenyl-4-yl-ethylamine 
• 1257846-35-7 1-methyl-3,4,6-triphenylisoquinoline 
• 223418-63-1 (S)-1-([1,1'-biphenyl]-4-yl)ethan-1-amine 
• 86217-67-6 N-<1-(4-Biphenylyl)ethyl>-cis-4,5-diphenyl-2-oxazolidone-3-carboxamide 

Relevant articles and documents

Rh(III)-catalyzed synthesis of isoquinolines using the N-Cl bond of N-chloroimines as an internal oxidant

The Rh(III)-catalyzed coupling of N-chloroimines with alkynes for the efficient synthesis of isoquinolines is reported. This represents the first use of the N-Cl bond of N-chloroimines as an internal oxidant for construction of the isoquinoline skeleton. The synthesis features atom and step economy, a green solvent (EtOH), mild reaction conditions, and a broad substrate scope.

Nano-Fe3O4@SiO2-SO3H: A magnetic, reusable solid-acid catalyst for solvent-free reduction of oximes to amines with the NaBH3CN/ZrCl4 system

In this study, the immobilization of sulfonic acid on silica-layered magnetite was carried out by the reaction of ClSO3H with silica-layered magnetite. The prepared magnetic nanoparticles of Fe3O4@SiO2-SO3H were then characterized using scanning electron microscopy, energy dispersive X-ray spectroscopy, X-ray diffraction, Fourier transform infrared spectroscopy, vibrating sample magnetometry, and transmission electron microscopy. The sulfonated nanocomposite exhibited excellent catalytic activity and reusability in the reduction of various aldoximes and ketoximes with NaBH3CN in the presence of ZrCl4. All reactions were carried out under solvent-free conditions (r.t. or 75–80°C) within 3–70 min to afford amines in high to excellent yields.

Rh(III)-Catalyzed Coupling of N-Chloroimines with α-Diazo-α-phosphonoacetates for the Synthesis of 2 H-Isoindoles

We report herein the first use of N-chloroimines as effective synthons for directed C-H functionalization. Rh(III)-catalyzed coupling of N-chloroimines with α-diazo-α-phosphonoacetates allows for efficient dechlorinative/dephosphonative access to 2H-isoindoles. Further deesterification under Ni(II) catalysis enables the complete elimination of reactivity-assisting groups and full exposure of reactivity of C3 and N2 ring atoms for attaching structurally distinct appendages.