871086-12-3

Basic information

• Product Name: Benzenesulfonamide, 4-methyl-N-[(1S,2S)-2-[[(1R)-1-phenylethyl]amino]cyclohexyl]-
• CAS NO: 871086-12-3
• Molecular Formula: C21H28N2O2S
• Molecular Weight: 372.532
• Mol File: 871086-12-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Benzenesulfonamide, 4-methyl-N-[(1S,2S)-2-[[(1R)-1-phenylethyl]amino]cyclohexyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenesulfonamide, 4-methyl-N-[(1S,2S)-2-[[(1R)-1-phenylethyl]amino]cyclohexyl]-(871086-12-3)
• EPA Substance Registry System: Benzenesulfonamide, 4-methyl-N-[(1S,2S)-2-[[(1R)-1-phenylethyl]amino]cyclohexyl]-(871086-12-3)

Safety Data

• Hazardous Substances Data: 871086-12-3(Hazardous Substances Data)

Upstream product

• 68820-12-2 cyclohexyl-N-tosyl aziridine 
• 3886-69-9 (R)-1-phenyl-ethyl-amine 

Downstream Products

• 174291-97-5 N-[(1S,2S)-2-aminocyclohexan-1-yl]-4-methylbenzenesulfonamide 
• 212555-28-7 (S,S)-N,N'-bis(p-tolylsulfonyl)-trans-cyclohexane-1,2-diamine 

Relevant articles and documents

Synthesis of chiral vicinal C2 symmetric and unsymmetric bis(sulfonamide) ligands based on trans-1,2-cyclohexanediamine by aminolysis of N-tosylaziridines

The ring opening of N-tosylaziridines with aliphatic amines can be efficiently catalyzed by lithium perchlorate to provide derivatives of the trans-1,2-diamine in high yields. The reaction was used in desymmetrization of several cyclic N-tosylaziridines using chiral amines. Using this strategy, an efficient synthesis of chiral vicinal C2 symmetric bis(sulfonamide) and unsymmetrical bis(sulfonamide) ligands based on trans-1,2-cyclohexanediamine was developed.