912838-01-8

Basic information

• Product Name: butyl 5-(3-buten-1-yl)-1-{4-[(tert-butoxycarbonyl)amino]phenyl}-1H-1,2,3-triazole-4-carboxylate
• Synonyms: butyl 5-(3-buten-1-yl)-1-{4-[(tert-butoxycarbonyl)amino]phenyl}-1H-1,2,3-triazole-4-carboxylate
• CAS NO: 912838-01-8
• Molecular Weight: 414.505
• Mol File: 912838-01-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: butyl 5-(3-buten-1-yl)-1-{4-[(tert-butoxycarbonyl)amino]phenyl}-1H-1,2,3-triazole-4-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: butyl 5-(3-buten-1-yl)-1-{4-[(tert-butoxycarbonyl)amino]phenyl}-1H-1,2,3-triazole-4-carboxylate(912838-01-8)
• EPA Substance Registry System: butyl 5-(3-buten-1-yl)-1-{4-[(tert-butoxycarbonyl)amino]phenyl}-1H-1,2,3-triazole-4-carboxylate(912838-01-8)

Safety Data

• Hazardous Substances Data: 912838-01-8(Hazardous Substances Data)

Upstream product

• 30414-57-4 methyl 3-oxohept-6-enoate 
• 71026-66-9 N-(tert-butoxycarbonyl)-1,4-phenylenediamine 
• 79791-38-1 4-dodecylbenzenesulphonyl azide 

Relevant articles and documents

TRIAZOLE DERIVATIVE AND THE USE THEREOF

The present invention relates to a thrombin receptor antagonist containing a compound represented by the formula (I) wherein R1a, R1b and R2 are each a hydrogen atom, an optionally substituted hydrocarbon group, an optionally substituted heterocyclic group, or an optionally substituted alkoxy, R3 is a group represented by the formula -NHCOR4, -NHSO2R5, -NHCON(R6a) (R6b), -NHCOOR7 or -CONHR8 wherein R4, R5, R6a, R6b, R7 and R8 are each a hydrogen atom, an optionally substituted hydrocarbon group, an optionally substituted heterocyclic group and the like), ring A is monocyclic aromatic ring optionally further having substituent(s), R1a and R1b are optionally bonded to each other to form an optionally substituted nitrogen-containing non-aromatic heterocycle, or a salt thereof or a prodrug thereof. The thrombin receptor antagonist of the present invention has a thrombin receptor (particularly PAR-1) antagonistic action and is useful for the prophylaxis or treatment of PAR-1 mediated pathological condition or disease.