93830-58-1

Basic information

• Product Name: Pyridine, 4-(diethylboryl)-
• Synonyms: Pyridine, 4-(diethylboryl)-;Diethyl (pyridin-4-yl)borane;diethyl(4-pyridyl)borane
• CAS NO: 93830-58-1
• Molecular Formula: C₉H₁₄BN
• Molecular Weight: 147.02516
• EINECS: -0
• Mol File: 93830-58-1.mol
• Article Data: 3

Chemical Properties

• Melting Point: >300 °C(Solv: acetone (67-64-1))
• Boiling Point: 205.9±22.0 °C(Predicted)
• Appearance: /
• Density: 0.86±0.1 g/cm3(Predicted)
• PKA: 5.08±0.10(Predicted)
• CAS DataBase Reference: Pyridine, 4-(diethylboryl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Pyridine, 4-(diethylboryl)-(93830-58-1)
• EPA Substance Registry System: Pyridine, 4-(diethylboryl)-(93830-58-1)

Safety Data

• Hazardous Substances Data: 93830-58-1(Hazardous Substances Data)

Usage

Description

Pyridine, 4-(diethylboryl)-, also known as Diethyl(pyridin-4-yl)borane, is an organic compound that features a pyridine ring with a diethylboryl group attached at the 4-position. Pyridine, 4-(diethylboryl)is known for its strong reducing properties, making it a valuable reagent in various chemical reactions.

Uses

Used in Pharmaceutical Industry:
Pyridine, 4-(diethylboryl)is used as a reducing agent for the synthesis of non-basic compounds, specifically as factor Xa inhibitors. These inhibitors play a crucial role in the development of anticoagulant medications, which help prevent blood clots and related health issues.
Used in Organic Synthesis:
In the field of organic synthesis, Pyridine, 4-(diethylboryl)is utilized for the synthesis of 4-aryland 4-heteroarylpyridines. This is achieved through the palladium-catalyzed cross-coupling reaction, a widely used method for forming carbon-carbon bonds in organic chemistry. The resulting 4-aryland 4-heteroarylpyridines have potential applications in various areas, such as pharmaceuticals, agrochemicals, and materials science, due to their diverse chemical properties and potential biological activities.

Upstream product

• 1120-87-2 4-bromopyridin 
• 7397-46-8 diethyl methoxy borane 
• 97-94-9 triethyl borane 

Downstream Products

• 21308-82-7 4-(thiophen-3-yl)-pyridine 
• 581-47-5 4-(2-pyridyl)pyridine 
• 106047-21-6 5-methyl-2,4'-bipyridine 
• 106047-38-5 3-bromo-5-(4-pyridyl)pyridine 
• 106047-37-4 4,3′:5′,4″-terpyridine 
• 70650-95-2 [4,2’;6’,4”]-terpyridine 
• 106047-29-4 2-bromo-6-(pyridin-4-yl)pyridine 
• 106047-33-0 5-bromo-2,4′-bipyridine 
• 5957-96-0 4-(4-chlorophenyl)pyridine 
• 52089-02-8 2-(pyridin-4-yl)quinoline 
• 939-23-1 p-phenylpyridine 
• 5938-16-9 4-(4-methoxylphenyl)pyridine 
• 5958-00-9 4-(2-methoxylphenyl)pyridine 
• 106047-16-9 methyl 2-(4-pyridyl)benzoate 

Relevant articles and documents

Cathodic electrochromic compound used in electrochromic device, and preparation method thereof

The structural formula of a cathodic electrochromic compound is shown in the description, a pyridine ring in the middle of the cathodic electrochromic compound is connected to any carbon atom in pyridine rings at two sides through a C-C bond; and in the formula, R1 is selected from C2-20 alkyl groups, R2 to R12 are substituent groups on carbon atoms and are respectively independently selected from H, C1-50 alkyl groups, cycloalkyl groups, polycycloalkyl groups, aryl groups, heterocycloalkyl groups, aralkyl groups and alkaryl groups which are free from or contain halogen, N, O, S, Si, P or an unsaturated bond, and X is selected from a methylbenzenesulfonate anion, a tetrafluoroborate anion, a hexafluoroborate anion, a perchlorate anion, a bisoxalatoborate anion, an oxalyldifluroborate anion, a bis(trifluoromethanesulphonyl)imide anion and a tris(trifluoromethanesulfonyl)methyl anion. An electrochromic device using the compound has a long service life and a deep color, and can greatly reduce the visible light transmittance in the power-up state.

Indole derivatives as 5-HT1 -like agonists

The present invention provides compounds of the formula: STR1 and pharmaceutically acceptable salts thereof.