DIMETHYL-PARA-PHENYLENEDIAMINEHYDROCHLORIDE

Base Information

• Chemical Name: DIMETHYL-PARA-PHENYLENEDIAMINEHYDROCHLORIDE
• CAS No.: 105-10-2
• Molecular Formula: C8H12 N2
• Molecular Weight: 136.197
• Hs Code.: 2921519090
• Mol file: 105-10-2.mol

Synonyms:1,4-Benzenediamine,N,N'-dimethyl- (9CI); p-Phenylenediamine, N,N'-dimethyl- (7CI,8CI); Alarmine;N,N'-Dimethyl-1,4-phenylenediamine; N,N'-Dimethyl-p-phenylenediamine;N,N'-Dimethylbenzene-1,4-diamine

Chemical Property of DIMETHYL-PARA-PHENYLENEDIAMINEHYDROCHLORIDE

Chemical Property:

• Vapor Pressure: 0.0112mmHg at 25°C
• Melting Point: 53°C
• Refractive Index: 1.5180 (estimate)
• Boiling Point: 262°Cat760mmHg
• Flash Point: 88.6°C
• PSA: 24.06000
• Density: g/cm³
• LogP: 1.91600
• Storage Temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
• Solubility.: Chloroform, DMSO, Ethyl Acetate

Purity/Quality:

98%,99%, ^*data from raw suppliers

Alarmine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: A degradation product of mutagenic Acid orange 52 by plasid DNA damage.

Technology Process of DIMETHYL-PARA-PHENYLENEDIAMINEHYDROCHLORIDE

There total 13 articles about DIMETHYL-PARA-PHENYLENEDIAMINEHYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.5%

1.4-dibromobenzene (106-37-6) + methylamine (74-89-5) → N,N'-dimethyl-p-phenylenediamine (105-10-2)

Guidance literature:

With copper; In water; at 100 ℃; for 16h;

DOI:10.1021/jo102169t

Reference yield: 88.0%

methanol (67-56-1) + 1,4-phenylenediamine (106-50-3) → N,N'-dimethyl-p-phenylenediamine (105-10-2)

Guidance literature:

With [((5-Me)PyNPPh₂)IrACHTUNGTRENUNG(cod)]; potassium tert-butylate; In diethylene glycol dimethyl ether; at 70 ℃; for 48h; Inert atmosphere;

DOI:10.1002/adsc.201100554

Reference yield: 78.4%

N,N'-dimethyl-N,N'-di-p-toluenesulfonyl-1,4-phenylenediamine (56077-38-4) → N,N'-dimethyl-p-phenylenediamine (105-10-2)

Guidance literature:

With hydrogen bromide; phenol; In water; for 1h; Reflux;

DOI:10.1002/ejoc.200900403

upstream raw materials:

N,N'-dimethyl-N,N'-di-p-toluenesulfonyl-1,4-phenylenediamine

hydroquinone

methylamine

N-(4-formylaminophenyl)formamide

Downstream raw materials:

1,4-bis-[methyl-(3-nitro-benzenesulfonyl)-amino]-benzene

1,3,1',3'-tetramethyl-1,1'-p-phenylene-bis-thiourea

N,N'-dimethyl-N,N'-dinitroso-p-phenylenediamine

N,N'-bis[3-tert-butyl-5-(N-(tert-butyldimethylsiloxy)-N-tert-butylamino)phenyl]-N,N'-dimethyl-p-phenylenediamine

Refernces

• 1、 -. "COLLECTIONS OF PEPTIDES, PEPTIDE AGENTS, AND METHODS OF USE THEREOF". Paragraph 0345; 0349. . Retrieved 2020/03/15.
• 2、 -. "Synthesis method of N-methylamine compound". Paragraph 0079-0082. . Retrieved 2018/09/08.