1-Methylpyridinium chloride

Base Information

• Chemical Name: 1-Methylpyridinium chloride
• CAS No.: 7680-73-1
• Molecular Formula: C6H8 N . Cl
• Molecular Weight: 129.589
• Hs Code.: 2933399090
• European Community (EC) Number: 231-658-9
• UNII: LRK3W477YB
• DSSTox Substance ID: DTXSID50932185
• Mol file: 7680-73-1.mol

Synonyms:1-methylpyridinium;1-methylpyridinium chloride;1-methylpyridinium dibromoiodate (1-);1-methylpyridinium iodide;1-methylpyridinium mu-iodotetraiododimercurate (1-);N-methylpyridinium

Chemical Property of 1-Methylpyridinium chloride

Chemical Property:

• Melting Point: 144 °C
• PSA: 3.88000
• LogP: -2.48490
• Storage Temp.: Hygroscopic, Refrigerator, under inert atmosphere
• Solubility.: Methanol (Slightly), Water
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 129.0345270
• Heavy Atom Count: 8
• Complexity: 46.1

Purity/Quality:

98%, ^*data from raw suppliers

1-Methylpyridinium Chloride ^*data from reagent suppliers

Safty Information:

• Statements: 20/21/22-36/37/38
• Safety Statements: 36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C[N+]1=CC=CC=C1.[Cl-]
• Uses: 1-Methyl-pyridinium Chloride is a degradation product of pralidoxime chloride (P701120) in concentrated acidic solution. pralidoxime chloride (P701120) binds to inactivated acetylcholinesterases and is used to combat poisoning from organophosphates and nerve agents .

Technology Process of 1-Methylpyridinium chloride

There total 15 articles about 1-Methylpyridinium chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

N-methylpyridinium p-toluenesulfonate (38542-71-1) → N-methylpyridinium chloride (7680-73-1)

Guidance literature:

With Dowex 1-X₈ (Cl) 100-200 mesh standard grade resin; In water; Inert atmosphere;

DOI:10.1039/b906409e

Reference yield: 46.0%

→ N-methylpyridinium chloride (7680-73-1)

Guidance literature:

Reference yield: 21.0%

pyridine (110-86-1) + N,N-dimethoxyamine (88470-26-2) → N-methylpyridinium chloride (7680-73-1)

Guidance literature:

With tert-butylhypochlorite; In diethyl ether; at -78 - -8 ℃;

DOI:10.1016/S0040-4020(01)81731-2

upstream raw materials:

pyridine

methylene chloride

pyridine hydrochloride

2-methoxy-1,3-dioxane

Downstream raw materials:

pyridine

N-methylcyclohexylamine

[N-methylpyridinium][Au(triphenylphosphine)(2-((4,5-ethylenedithio)-1,3-dithiole-2-ylidene)-1,3-dithiole-4,5-dithionato)]

N-methyl-3,4-didehydropiperidine

Refernces

• 1、 Verevkin, Sergey P.,Zaitsau, Dzmitry H.,Emel'Yanenko, Vladimir N.,Ralys, Ricardas V.,Yermalayeu, Andrei V.,Schick, Christoph. "Does alkyl chain length really matter? Structure-property relationships in thermochemistry of ionic liquids". . p. 84 - 95. Retrieved 2013/07/28.
• 2、 Stadler, Richard H,Varga, Natalia,Hau, Joerg,Vera, Francia Arce,Welti, Dieter H. "Alkylpyridiniums. 1. Formation in model systems via thermal degradation of trigonelline.". . p. 1192 - 1199. Retrieved 2007/10/03.