α-methoxy-α,α'-dihydrobenzocyclobutene

Base Information

• Chemical Name: α-methoxy-α,α'-dihydrobenzocyclobutene
• CAS No.: 36101-23-2
• Molecular Formula: C₉H₁₀O
• Molecular Weight: 134.178
• Mol file: 36101-23-2.mol

Synonyms:

Chemical Property of α-methoxy-α,α'-dihydrobenzocyclobutene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of α-methoxy-α,α'-dihydrobenzocyclobutene

There total 11 articles about α-methoxy-α,α'-dihydrobenzocyclobutene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-(Methoxymethyl)benzaldehyde tosylhydrazone (119367-60-1) → 1,3-dihydroisobenzofuran (496-14-0) + isochromane (493-05-0) + α-methoxy-α,α'-dihydrobenzocyclobutene (36101-23-2,52665-63-1) + 1-tert-Butoxymethyl-2-methoxymethyl-benzene (119367-61-2)

Guidance literature:

With potassium tert-butylate; In tert-butyl alcohol; for 2h; Yield given. Further byproducts given. Yields of byproduct given; Ambient temperature; Irradiation;

DOI:10.1021/ja00186a048

Reference yield:

2-(Methoxymethyl)benzaldehyde tosylhydrazone (119367-60-1) → 1,3-dihydroisobenzofuran (496-14-0) + 2-methoxymethyltoluene (15018-12-9) + α-methoxy-α,α'-dihydrobenzocyclobutene (36101-23-2,52665-63-1) + 1-(Ethoxymethyl)-2-(methoxymethyl)benzene (119367-57-6)

Guidance literature:

With sodium ethanolate; In ethanol; for 2h; Yield given. Further byproducts given. Yields of byproduct given; Ambient temperature; Irradiation;

DOI:10.1021/ja00186a048

Reference yield:

methanol (67-56-1) + 2-(Methoxymethyl)benzaldehyde tosylhydrazone (119367-60-1) → 1,3-dihydroisobenzofuran (496-14-0) + 2-methoxymethyltoluene (15018-12-9) + α-methoxy-α,α'-dihydrobenzocyclobutene (36101-23-2,52665-63-1) + 1,2-bis(methoxymethyl)benzene (5707-27-7)

Guidance literature:

With sodium methylate; for 2h; Yield given. Further byproducts given. Yields of byproduct given; Ambient temperature; Irradiation;

DOI:10.1021/ja00186a048

upstream raw materials:

methanol

2-(Methoxymethyl)benzaldehyde tosylhydrazone

ethanol

diethylene glycol dimethyl ether

Refernces