374538-03-1 Usage
Description
2-Methoxycarbonylphenylboronic acid is an organic compound with the chemical formula C8H9BO4. It is a white to brown powder that may contain varying amounts of anhydride. 2-Methoxycarbonylphenylboronic acid is known for its unique chemical properties and potential applications in various industries.
Uses
Used in Pharmaceutical Industry:
2-Methoxycarbonylphenylboronic acid is used as a key intermediate in the synthesis of various pharmaceutical compounds. Its unique structure allows it to be a versatile building block for the development of new drugs with potential therapeutic applications.
Used in Chemical Synthesis:
In the field of chemical synthesis, 2-Methoxycarbonylphenylboronic acid serves as a valuable reagent for the preparation of various organic compounds. Its boronic acid group enables it to participate in a range of chemical reactions, making it a useful component in the synthesis of complex organic molecules.
Used in Material Science:
2-Methoxycarbonylphenylboronic acid is also utilized in material science for the development of new materials with specific properties. Its ability to form stable bonds with other molecules allows it to be incorporated into the design of advanced materials with potential applications in various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 374538-03-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,7,4,5,3 and 8 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 374538-03:
(8*3)+(7*7)+(6*4)+(5*5)+(4*3)+(3*8)+(2*0)+(1*3)=161
161 % 10 = 1
So 374538-03-1 is a valid CAS Registry Number.
InChI:InChI=1/C8H9BO4/c1-13-8(10)6-4-2-3-5-7(6)9(11)12/h2-5,11-12H,1H3
374538-03-1Relevant articles and documents
Method for synthesizing sodium 2-carboxyphenylborate
-
Paragraph 0015; 0018, (2020/06/17)
The invention discloses a method for synthesizing sodium 2-carboxyphenylborate. The method comprises the following two steps of: 1) taking methyl 2-bromobenzoate as an initial raw material, through bromine removal by butyl lithium, carrying out a one-pot reaction with triisopropyl borate or trimethyl borate to obtain a product 2-methoxycarbonyl phenylboronic acid, and 2) hydrolyzing the 2-methoxycarbonyl phenylboronic acid in a sodium hydroxide methanol solution, and pulping with acetone to obtain sodium 2-carboxyphenylborate monohydrate. The method has the advantages of easily available raw materials, simple operation, safety, environmental protection, low cost and high yield.
Noncryogenic I/Br-Mg exchange of aromatic halides bearing sensitive functional groups using i-PrMgCl-Bis[2-(N,N-dimethylamino)ethyl] ether complexes
Wang, Xiao-Jun,Sun, Xiufeng,Zhang, Li,Xu, Yibo,Krishnamurthy, Dhileepkumar,Senanayake, Chris H.
, p. 305 - 307 (2007/10/03)
Iodo- and bromoaromatics bearing sensitive carboxylic ester and cyano groups underwent a selective halide-magnesium exchange with isopropylmagnesium chloride at ambient temperature in the presence of bis[2-(N,N-dimethylamino) ethyl] ether to afford the corresponding Grignard reagents. The newly formed reactive Grignard reagents were allowed to react with electrophiles such as trimethylborate to afford arylboronic acids in good to excellent yields.
