701-70-2

Basic information

• Product Name: 1-PHENYL-2-BUTANOL
• Synonyms: 1-PHENYL-2-BUTANOL;AURORA KA-6967;2-Butanol, 1-phenyl-;alpha-ethyl-benzeneethano;alpha-Ethylbenzeneethanol;Benzyl ethyl carbinol;Phenethyl alcohol, alpha-ethyl-;1-phenylbutan-2-ol
• CAS NO: 701-70-2
• Molecular Formula: C₁₀H₁₄O
• Molecular Weight: 150.22
• EINECS: 211-858-2
• Product Categories: Alcohols;Building Blocks;C9 to C10;Chemical Synthesis;Organic Building Blocks;Oxygen Compounds
• Mol File: 701-70-2.mol
• Article Data: 70

Chemical Properties

• Boiling Point: 124-127 °C25 mm Hg(lit.)
• Flash Point: 212 °F
• Appearance: /
• Density: 0.989 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.0459mmHg at 25°C
• Refractive Index: n20/D 1.516(lit.)
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 15.24±0.20(Predicted)
• CAS DataBase Reference: 1-PHENYL-2-BUTANOL(CAS DataBase Reference)
• NIST Chemistry Reference: 1-PHENYL-2-BUTANOL(701-70-2)
• EPA Substance Registry System: 1-PHENYL-2-BUTANOL(701-70-2)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• Safety Statements: 24/25
• WGK Germany: 3
• Hazardous Substances Data: 701-70-2(Hazardous Substances Data)

Usage

Description

1-PHENYL-2-BUTANOL, also known as α-Ethylphenethyl alcohol, is an organic compound with the chemical formula C10H14O. It is a clear pale yellow liquid and is commonly utilized in chemical synthesis due to its versatile structure and properties.

Uses

1. Used in Chemical Synthesis:
1-PHENYL-2-BUTANOL is used as a key intermediate in the synthesis of various organic compounds, including pharmaceuticals, agrochemicals, and other specialty chemicals. Its unique structure allows for a wide range of reactions, making it a valuable building block in the chemical industry.
2. Used in Flavor and Fragrance Industry:
1-PHENYL-2-BUTANOL is used as a component in the creation of artificial flavors and fragrances, particularly those with a floral or fruity scent. Its pleasant aroma and stability make it a popular choice for use in the perfumery and flavoring agents.
3. Used in the Cosmetics Industry:
1-PHENYL-2-BUTANOL is employed as a solvent and fixative in the formulation of cosmetics, such as perfumes, colognes, and other personal care products. Its ability to dissolve a variety of substances and enhance the longevity of fragrances makes it an essential ingredient in the cosmetics sector.
4. Used in the Plastics and Polymer Industry:
1-PHENYL-2-BUTANOL is utilized as a monomer in the production of certain types of polymers and plastics. Its chemical properties allow it to be copolymerized with other monomers, resulting in materials with specific characteristics, such as improved strength, flexibility, or durability.
5. Used in the Dyes and Pigments Industry:
1-PHENYL-2-BUTANOL is used as a starting material in the synthesis of various dyes and pigments, particularly those with vibrant colors and high stability. Its versatility in chemical reactions enables the production of a wide range of colorants for use in various applications, such as textiles, paints, and inks.

InChI:InChI=1/C10H14O/c1-2-10(11)8-9-6-4-3-5-7-9/h3-7,10-11H,2,8H2,1H3/t10-/m1/s1

Upstream product

• 925-90-6 ethylmagnesium bromide 
• 122-78-1 phenylacetaldehyde 
• 123-38-6 propionaldehyde 
• 6921-34-2 benzylmagnesium chloride 
• 106-88-7 ethyloxirane 
• 591-50-4 iodobenzene 
• 1007-32-5 benzyl ethyl ketone 
• 4436-24-2 1,2-epoxy-3-phenylpropane 
• 75-24-1 trimethylaluminum 
• 29429-58-1 tetramethyldialuminoxane 
• 27846-25-9 1-phenyl-2-(phenylsulfonyl)ethane 
• 97-94-9 triethyl borane 
• 6052-66-0 1-phenyl-3-buten-2-ol 
• 74-96-4 ethyl bromide 

Downstream Products

• 128126-07-8 (3,5-Dinitro-phenyl)-carbamic acid (R)-1-benzyl-propyl ester 
• 128126-07-8 (3,5-Dinitro-phenyl)-carbamic acid (S)-1-benzyl-propyl ester 
• 1007-32-5 benzyl ethyl ketone 
• 24767-68-8 1-chloro-1-phenylbutan-2-one 
• 24767-67-7 3-chloro-1-phenyl-2-butanone 
• 38321-65-2 Thiobenzoesaeure-O-1-benzyl-propylester 
• 86527-08-4 (R,S)-1-phenyl-2-butyl acetate 
• 824-90-8 1-phenylbut-1-ene 
• 959082-23-6 1-(1-phenylbut-2-yl)-2-phenylsulfonylindole 
• 959107-21-2 C₂₄H₂₃NO₂S 
• 1243565-51-6 1-(1-phenylbut-2-yl)indole 
• 81012-82-0 (2-bromobutyl)benzene 
• 1271984-17-8 C₁₁H₁₄O₂ 
• 29393-19-9 (2R)-1-phenylbutan-2-ol 

Relevant articles and documents

Direct and Unified Access to Carbon Radicals from Aliphatic Alcohols by Cost-Efficient Titanium-Mediated Homolytic C?OH Bond Cleavage

Low-valent Ti-mediated homolytic C?O bond cleavage offers unified access to carbon radicals from ubiquitous non-activated tertiary, secondary, and even primary alcohols. In contrast to the representative Ti reagents, which were ineffective for this purpos

Regiodivergent Hydroborative Ring Opening of Epoxides via Selective C-O Bond Activation

A magnesium-catalyzed regiodivergent C-O bond cleavage protocol is presented. Readily available magnesium catalysts achieve the selective hydroboration of a wide range of epoxides and oxetanes yielding secondary and tertiary alcohols in excellent yields and regioselectivities. Experimental mechanistic investigations and DFT calculations provide insight into the unexpected regiodivergence and explain the different mechanisms of the C-O bond activation and product formation.

A General Regioselective Synthesis of Alcohols by Cobalt-Catalyzed Hydrogenation of Epoxides

A straightforward methodology for the synthesis of anti-Markovnikov-type alcohols is presented. By using a specific cobalt triphos complex in the presence of Zn(OTf)2 as an additive, the hydrogenation of epoxides proceeds with high yields and selectivities. The described protocol shows a broad substrate scope, including multi-substituted internal and terminal epoxides, as well as a good functional-group tolerance. Various natural-product derivatives, including steroids, terpenoids, and sesquiterpenoids, gave access to the corresponding alcohols in moderate-to-excellent yields.