Pentanedinitrile, 3-phenyl-

Base Information

• Chemical Name: Pentanedinitrile, 3-phenyl-
• CAS No.: 78533-73-0
• Molecular Formula: C11H10N2
• Molecular Weight: 170.214
• Mol file: 78533-73-0.mol

Synonyms:

Chemical Property of Pentanedinitrile, 3-phenyl-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Pentanedinitrile, 3-phenyl-

There total 8 articles about Pentanedinitrile, 3-phenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

benzaldehyde (100-52-7) + cyanoacetic acid (372-09-8) → 3-phenylglutaronitrile (78533-73-0)

Guidance literature:

With piperidine; pyridine; for 12h; Reflux;

DOI:10.1002/adsc.201800956

Reference yield:

benzaldehyde (100-52-7) + acetonitrile (75-05-8,26809-02-9) → 3-phenylglutaronitrile (78533-73-0) + dihydrocinnamonitrile (645-59-0)

Guidance literature:

With N,N,N,N-tetraethylammonium tetrafluoroborate; at 23 ℃; for 0.418333h; electrolysis;

Reference yield:

cinnamic nitrile (1885-38-7) + acetonitrile (75-05-8,26809-02-9) → C18H16N2 (1132799-51-9) + 3,4-diphenyl-adiponitrile (18891-12-8) + 3-phenylglutaronitrile (78533-73-0) + dihydrocinnamonitrile (645-59-0)

Guidance literature:

With N,N,N,N-tetraethylammonium tetrafluoroborate; at 24.84 ℃; Title compound not separated from byproducts.; Electrochemical reaction;

DOI:10.1071/CH08092

upstream raw materials:

pyridine

benzaldehyde

cyanoacetic acid

acetonitrile

Downstream raw materials:

(3S)-4-cyano-3-phenylbutanoic acid

(S)-4-Carbamoyl-3-phenyl-butyric acid

((R)-3-Cyano-2-phenyl-propyl)-carbamic acid methyl ester

(S)-Phenibut

Refernces

• 1、 Wang, Huan,Lin, Mei-Yu,Zhang, Kai,Li, Su-Jiao,Lu, Jia-Xing. "Electrochemical reduction of cinnamonitrile in the presence of carbon dioxide: Synthesis of cyano- and phenyl-substituted propionic acids". . p. 526 - 530. Retrieved 2008/12/20.
• 2、 Bellamy, Anthony J.,Kerr, John B.,McGregor, CChristopher J.,MacKirdy, Iain S.. "Cyanomethylation versus Reductive Saturation and Hydrodimerisation during the Electroreduction αβ-Unsaturated Nitriles in Acetonitriles". . p. 161 - 168. Retrieved 2007/10/02.