33687-74-0

Basic information

• Product Name: 2-methyl-2-nitro-1-phenylpropan-1-ol
• Synonyms: 2-Methyl-2-nitro-1-phenylpropan-1-ol; Benzenemethanol, .alpha.- (1-methyl-1-nitroethyl)-; Benzenemethanol, .alpha.-(1-methyl-1-nitroethyl)-; benzenemethanol, alpha-(1-methyl-1-nitroethyl)-; Benzyl alcohol, .alpha.- (1-methyl-1-nitroethyl)-; Benzyl alcohol, .alpha.-(1-methyl-1-nitroethyl)-
• CAS NO: 33687-74-0
• Molecular Formula: C₁₀H₁₃NO₃
• Molecular Weight: 195.2151
• Mol File: 33687-74-0.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 324.9°C at 760 mmHg
• Flash Point: 139.4°C
• Density: 1.173g/cm³
• Vapor Pressure: 9.72E-05mmHg at 25°C
• Refractive Index: 1.545
• CAS DataBase Reference: 2-methyl-2-nitro-1-phenylpropan-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-methyl-2-nitro-1-phenylpropan-1-ol(33687-74-0)
• EPA Substance Registry System: 2-methyl-2-nitro-1-phenylpropan-1-ol(33687-74-0)

Safety Data

• Hazardous Substances Data: 33687-74-0(Hazardous Substances Data)

Upstream product

• 79-46-9 2-nitropropane 
• 100-52-7 benzaldehyde 
• 100-39-0 benzyl bromide 
• 5447-97-2 2-bromo-2-nitropropane 
• 69119-37-5 2-aci-nitropropane (t-butyl)dimethylsilyl ester 

Downstream Products

• 68385-34-2 N-(2-hydroxy-1,1-dimethyl-2-phenylethyl)hydroxylamine 
• 34405-42-0 α-(1-amino-1-methylethyl)benzenemethanol 
• 79-46-9 2-nitropropane 
• 100-52-7 benzaldehyde 
• 180081-15-6 tert-butyl N-[2-methyl-1-(4-nitrophenyl)-2-propyl]carbamate 
• 82408-64-8 N-(1,1-dimethyl-2-(4-nitrophenyl)ethyl)amine 
• 122-09-8 Phentermin 
• 1198312-18-3 C₂₁H₂₉N₃O₄S 
• 1198312-16-1 C₂₁H₂₇N₃O₆S 
• 180081-16-7 N-(2-(4-aminophenyl)-1,1-dimethylethyl)carbamic acid t-butyl ester 
• 611-70-1 phenyl isopropyl ketone 
• 65-85-0 benzoic acid 
• 904325-61-7 N-allyl O-(2-methyl-2-nitro-1-phenylpropyl) O-phenyl phosphoramidate 

Relevant articles and documents

Novel synthetic approach to 1α,24(R)-dihydroxyvitamin D3 using an asymmetric nitroaldol reaction

Rare earth-K-(S)-BINOL complexes were used to catalyze the nitroaldol reaction of the CD-ring 24-aldehyde precursors with 2-nitropropane in a good stereoselective manner. The obtained nitroaldol compound was easily converted into a synthetic intermediate

Benzenesulfonyl-Asymmetric Ureas and Medical Uses Thereof

Benzenesulfonyl-asymmetric ureas are provided for the treatment of conditions modulated by the ghrelin receptor.

Indium-mediated reaction of 1-bromo-1-nitroalkanes with aldehydes: Access to 2-nitroalkan-1-ols

A novel method for the preparation of 2-nitroalkan-1-ols by an indium-promoted reaction of bromonitromethane with a variety of aldehydes is reported. The reaction was also performed with 2-bromo-2-nitropropanes to afford 2,2-dialkyl-2-nitroalkan-1-ols. The use of chiral sugar-derived aldehydes furnished the corresponding 2-nitroalkan-1-ols with excellent stereoselectivity. The utility of the novel sugar-derived 2,2-dialkyl-2-nitroalkan-1-ols for the preparation of branched iminosugar derivatives was demonstrated by the preparation of a hydroxymethyl branched polyhydroxylated azepane.