34405-42-0 Usage
Description
2-AMINO-2-METHYL-1-PHENYL-PROPAN-1-OL, also known as β-Hydroxyl Phentermine, is a compound derived from 2-Nitropropane (N519600). It is characterized by its ability to induce oxidative stress and has been identified as a carcinogen. This organic compound has unique properties that make it a subject of interest in various scientific and medical applications.
Uses
Used in Pharmaceutical Research:
2-AMINO-2-METHYL-1-PHENYL-PROPAN-1-OL is used as a research compound for its role in inducing DNA polymerase β-dependent base excision repair in response to oxidative stress in the liver. This application is significant for understanding the mechanisms of cellular response to oxidative damage and potentially developing treatments for related conditions.
Used in Toxicology Studies:
As a known carcinogen, 2-AMINO-2-METHYL-1-PHENYL-PROPAN-1-OL is utilized in toxicology studies to investigate the effects of carcinogens on biological systems. This helps in the development of preventive measures and treatments for cancer and other diseases associated with oxidative stress.
Used in Chemical Synthesis:
In the field of chemical synthesis, 2-AMINO-2-METHYL-1-PHENYL-PROPAN-1-OL may serve as a starting material or intermediate for the production of other pharmaceuticals or chemical compounds with various applications.
Check Digit Verification of cas no
The CAS Registry Mumber 34405-42-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,4,4,0 and 5 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 34405-42:
(7*3)+(6*4)+(5*4)+(4*0)+(3*5)+(2*4)+(1*2)=90
90 % 10 = 0
So 34405-42-0 is a valid CAS Registry Number.
InChI:InChI=1/C10H15NO/c1-10(2,11)9(12)8-6-4-3-5-7-8/h3-7,9,12H,11H2,1-2H3
34405-42-0Relevant articles and documents
Benzenesulfonyl-Asymmetric Ureas and Medical Uses Thereof
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Paragraph 0198; 0200, (2017/10/10)
Benzenesulfonyl-asymmetric ureas are provided for the treatment of conditions modulated by the ghrelin receptor.
Friedel-Crafts Acylation with N-(Trifluoroacetyl)-α-amino Acid Chlorides. Application to the Preparation of β-Arylalkylamines and 3-Substituted 1,2,3,4-Tetrahydroisoquinolines
Nordlander, Eric J.,Payne, Mark J.,Njoroge, George F.,Balk, Michael A.,Laikos George D.,Vishwanath, Vasanth M.
, p. 4107 - 4111 (2007/10/02)
Several N-(trifluoroacetyl)-α-amino acid chlorides have been reacted with benzene, anisole, and veratrole in the presence of AlCl3 or SnCl4 to produce the corresponding aromatic ketones in fair to high yields.The products are reductible under neutral or acidic conditions to the corresponding N-(trifluoroacetyl)-β-hydroxy-β-arylakylamines or N-(trifluoroacetyl)-β-arylalkylamines.The latter can be readily detrifluoroacetylated by mild basic hydrolysis and thence converted to the corresponding 3-substituted 1,2,3,4-tetrahydroisoquinolines by condensation with formaldehyde.
Improved Nitroaldol Reactions and Reductive Routes to Vicinal Aminoalcohols
Colvin, Ernest W.,Beck, Albert K.,Seebach, Dieter
, p. 2264 - 2271 (2007/10/02)
Regioselective and flexible procedures are described for the preparation of a variety of protected vicinal nitroalcohols 1, 3, and 5 (see Scheme 5), as is an efficient method for their reduction to the corresponding vicinal aminoalcohols 2, 4 and 6.
